Art

J-GLOBAL ID：202102291133004273   Reference number：21A0195295

Chronic Tear Deficiency Sensitizes Transient Receptor Potential Vanilloid 1-Mediated Responses in Corneal Sensory Nerves

慢性涙液欠乏は角膜感覚神経における一過性受容体電位バニロイド1仲介応答を感作する【JST・京大機械翻訳】

Author (10)： Masuoka Takayoshi (Department of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Japan) ,  Yamashita Yuka (Department of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Japan) ,  Nakano Katsuya (Department of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Japan) ,  Takechi Kenshi (Department of Clinical Pharmacology and Therapeutics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Takechi Kenshi (Department of Drug Information Analysis, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Japan) ,  Niimura Takahiro (Department of Clinical Pharmacology and Therapeutics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Tawa Masashi (Department of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Japan) ,  He Qiang (Department of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Japan) ,  Ishizawa Keisuke (Department of Clinical Pharmacology and Therapeutics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Ishibashi Takaharu (Department of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Japan)
Material： Frontiers in Cellular Neuroscience (Web)
Volume： 14  Page： 598678  Publication year： 2020 
JST Material Number： U7064A  ISSN： 1662-5102  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Chronic tear deficiency enhanc...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0195295&from=J-GLOBAL&jstjournalNo=U7064A") }}

Thesaurus term： *electric potential ,  neuron ,  *cornea ,  *sensitization(immunology) ,  *receptor ,  *sensory nerve ,  guinea pig ,  local administration ,  immunohistochemistry ,  unsaturated fatty acid ,  phenolic compound ,  olefin compound ,  carboxamide ,  phenol ether
Semi thesaurus term： 痛覚過敏 ,  アゴニスト ,  アンタゴニスト ,  TRPV1 ,  侵害受容 , 【Automatic Indexing@JST】

Author keywords (5)： cornea ,  transient receptor potential vanilloid 1 (TRPV1) ,  trigeminal ganglion ,  lacrimal gland excision ,  cold-sensitive nerve

JST classification (1)： Receptors on cell membrane  (EF04030C)

Substance index (1)： Capsaicin

Reference (38)：

• AcostaM. C.LunaC.QuirceS.BelmonteC.GallarJ. (2013). Changes in sensory activity of ocular surface sensory nerves during allergic keratoconjunctivitis. Pain 154, 2353-2362. doi: 10.1016/j.pain.2013.07.01223867735
• AcostaM. C.LunaC.QuirceS.BelmonteC.GallarJ. (2014). Corneal sensory nerve activity in an experimental model of UV keratitis. Invest. Ophthalmol. Vis. Sci. 55, 3403-3412. doi: 10.1167/iovs.13-1377424787567
• AlamriA.BronR.BrockJ. A.IvanusicJ.J. (2015). Transient receptor potential cation channel subfamily V member 1 expressing corneal sensory neurons can be subdivided into at least three subpopulations. Front. Neuroanat. 9:71. doi: 10.3389/fnana.2015.0007126106303
• AlcaldeI.Íñigo-PortuguésA.González-GonzálezO.AlmarazL.ArtimeE.Morenilla-PalaoC.. (2018). Morphological and functional changes in TRPM8-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. J. Comp. Neurol. 526, 1859-1874. doi: 10.1002/cne.2445429664111
• BatesB. D.MitchellK.KellerJ. M.ChanC. C.SwaimW. D.YaskovichR.. (2010). Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist. Pain 149, 522-528. doi: 10.1016/j.pain.2010.03.02420403666

Terms in the title (11)： 慢性 ,  涙液 ,  欠乏 ,  角膜 ,  感覚神経 ,  受容体 ,  電位 ,  バニロイド ,  仲介 ,  応答 ,  感作