Pat

J-GLOBAL ID：202103015232609336

レチノイドの副作用に対する感受性の決定方法

Inventor： 天野 聡 ,  井上 恭子 ,  出田 立郎 ,  長▲崎▼ 正朗 ,  峯岸 直子
Applicant, Patent owner： 株式会社 資生堂
Agent (6)： 青木 篤 ,  三橋 真二 ,  渡辺 陽一 ,  中島 勝 ,  武居 良太郎 ,  津田 英直
Gazette classification：公開公報
Application number (International application number)：2019130064
Publication number (International publication number)：2021013328
Application date： Jul. 12, 2019
Publication date： Feb. 12, 2021
Summary：

【課題】遺伝子多型解析により遺伝要素に基づいて対象のレチノイドの副作用に対する感受性を決定する方法の提供。【解決手段】特定の遺伝子多型から選ばれる、少なくとも1の遺伝子多型を検出する工程、検出された遺伝子多型に基づき、レチノイドの副作用に対する感受性を決定する工程含む、レチノイドの副作用に対する感受性の決定方法。【選択図】図1

Claim (excerpt)：

以下の: rs11264256、rs12129712、rs79393875、rs77098893、rs117172861、rs189364622、rs142413201、rs16836262、rs10190756、rs143833788、rs367757001、rs146490521、rs149747233、rs142834469、rs35219727、rs180936202、rs192883707、rs74384211、chr3:145318006:T:C、rs150321408、rs188646953、、rs6451234、rs12153578、rs12522083、rs2504905、rs6924827、rs75473584、rs1874404、rs75979900、rs74756212、chr7:57761277:GA:G、rs376694855、rs190896232、chr7:62622355:ATATATATATATATATATATATATATATATATATATATATATT:A、rs141378112、rs148217145、rs118097902、rs144455233、rs80110077、rs77590716、rs182345837、rs182712478、rs148109217、rs114276193、rs76234757、rs150594929、rs583641、rs568982、rs151336244、rs74341477、rs74712856、rs76086616、rs72213476、rs199680407、rs140189230、chr12:13295924:ACTT:A、rs5803510、rs117870315、rs139534747、rs112399579、rs72641020、rs72641025、rs139806172、rs72641051、rs72641054、rs146458360、rs17267348、rs17188613、rs72641063、chr13:93364715:AAC:A、rs16947848、rs1933192、rs17267362、rs17267369、rs1933191、rs117349244、rs56865501、rs141950809、rs72641088、rs67937794、rs66904991、rs66498781、rs57888578、rs60005783、rs11838810、rs11838825、rs11839660、rs11840951、rs72641100、rs67037212、rs78226726、rs34407653、rs57660170、rs7994061、rs78510371、rs17267439、rs11291152、rs7325627、rs9589649、rs9523866、rs71815886、rs1932194、rs17188760、rs4924269、rs57779669、rs11631905、rs146603798、rs76981822、rs34365165、rs1862450、rs56124193、rs142249518、rs75365663、rs12609658、rs76798890、rs12610503、rs10417947、rs113242419、rs10423303、rs8112254、rs186658317、chr20:25335351:G:A、chr20:25362934:T:C、chr20:25699935:T:G、rs2837971、rs9981747、rs73366468、rs3215895、rs61084367、rs59874887、rs58795078、rs77353301、rs72751553、rs72751555、rs114562381、rs4667864、rs12692666、rs10207946、chr2:167027058:A:G、rs117922874、rs200162964、chr3:176034566:A:G、rs2303137、rs1010600、rs7381111、rs10077384、rs142644927、rs147831886、rs4484457、rs147835552、rs7735423、rs1820005、rs12332211、rs4362916、rs4386714、rs6881783、rs199982719、rs17155553、rs7731680、rs6596535、rs6596536、rs10058377、rs17155559、rs7734977、rs7701241、rs10479259、rs10062431、rs73195737、rs59531312、rs10054393、rs189936937、chr8:64870523:AT:A、rs56290508、rs56354846、rs16919204、rs71471143、rs72837632、rs2175925、rs148267634、rs12772593、rs11595562、rs72260862、rs71940964、rs11596080、rs7923098、rs11816602、rs17105050、rs34638006、rs10887463、rs10887464、rs7093187、rs7075763、rs7086187、rs11201523、rs883802、rs142939963、rs10887465、rs7074418、rs200756077、chr10:87020520:A:AG、chr10:87020524:AAAATG:A、rs12359344、rs11201526、rs11201527、rs11201528、rs34168904、rs35164626、rs7098463、rs11492856、rs7092376、rs12763173、rs12764075、rs11511546、rs28766011、rs11201537、rs36071582、rs2882516、rs10509517、rs12769551、rs11368758、rs7910468、rs12775803、rs66483968、rs11201552、rs11201553、rs7920425、chr10:87112822:GA:G、rs71471155、rs9663303、rs72840999、rs72841000、rs11025696、rs11025697、rs11517566、rs12789625、rs151088833、rs11025698、rs11025699、rs35230659、rs34391252、rs150667993、rs75905889、rs193002524、chr11:21747092:GTGTTTGTGTGTT:G、rs35565978、rs61556663、rs74030727、rs11073552、rs148027820、rs142595348、rs144638318、rs147470668、rs3851135、rs62129325、rs144365368、rs3988408、rs11437257、rs141791163、rs10008137、rs7832052、rs7845083、chr11:95462296:C:CAT、及びrs9978357からなる群から選ばれる、少なくとも1の遺伝子多型を検出する工程、 検出された遺伝子多型に基づき、レチノイドの副作用に対する感受性を決定する工程 を含む、レチノイドの副作用に対する感受性の決定方法。

IPC (2)：

C12Q 1/68 ,  C12Q 1/02

FI (2)：

C12Q1/68 ,  C12Q1/02

F-Term (12)：

4B063QA01 ,  4B063QA05 ,  4B063QA13 ,  4B063QA18 ,  4B063QQ42 ,  4B063QQ52 ,  4B063QR32 ,  4B063QR35 ,  4B063QS25 ,  4B063QS28 ,  4B063QS34 ,  4B063QX02

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