J-GLOBAL ID:202110003009594423   Research Resource code:NBDC02571 Update date:Jun. 30, 2021

SAGD: Sex-Associated Gene Database

SAGD: Sex-Associated Gene Database
Owning Organization:
  • College of Life Science and Technology, Huazhong Agricultural University
Resource classification: Data,Database
Tag (subject)  (1): Genome/Gene
Tag (data type)  (2): Expression ,  Distribution
Species (12): Bos taurus (NCBI Taxonomy ID: 9913) ,  Caenorhabditis (NCBI Taxonomy ID: 6237) ,  Danio rerio (NCBI Taxonomy ID: 7955) ,  Drosophila (NCBI Taxonomy ID: 7215) ,  Equus caballus (NCBI Taxonomy ID: 9796) ,  Gallus gallus (NCBI Taxonomy ID: 9031) ,  Homo sapiens (NCBI Taxonomy ID: 9606) ,  Macaca mulatta (NCBI Taxonomy ID: 9544) ,  Mus musculus (NCBI Taxonomy ID: 10090) ,  Pan troglodytes (NCBI Taxonomy ID: 9598) ,  Pristionchus pacificus (NCBI Taxonomy ID: 54126) ,  Rattus norvegicus (NCBI Taxonomy ID: 10116)
Many animal species present sex differences. Sex-associated genes (SAGs), which have female-biased or male-biased expression, have major influences on the remarkable sex differences in important traits such as growth, reproduction, disease resistance and behaviors. However, the SAGs resulting in the vast majority of phenotypic sex differences are still unknown. To provide a useful resource for the functional study of SAGs, we manually curated public RNA-seq datasets with paired female and male biological replicates from the same condition and systematically re-analyzed the datasets using standardized methods. We identified 27,793 female-biased SAGs and 64,043 male-biased SAGs from 2,828 samples of 21 species, including human, chimpanzee, macaque, mouse, rat, cow, horse, chicken, zebrafish, seven fly species and five worm species. All these data were cataloged into SAGD, a user-friendly database of SAGs where users can browse SAGs by gene, species, drug, and dataset. In SAGD, the expression, annotation, targeting drugs, homologs, ontology and related RNA-seq datasets of SAGs are provided to help researchers to explore their functions and potential applications in agriculture and human health.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

Return to Previous Page