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J-GLOBAL ID：202201002024641000   Update date: Sep. 13, 2024

Ibrahim Abd Aziz

イブラヒム アブドゥル アジズ | Ibrahim Abd Aziz
Affiliation and department：
Tokai University School of Medicine

About Tokai University School of Medicine


Job title： Senior Lecturer
Research theme for competitive and other funds  (6)：
  • 2023 - 2027 Elucidation of stem cell motility mechanism and its application to regeneration and cancer therapy
  • 2021 - 2025 線溶系制御因子を標的とした新規複合的がん免疫療法の確立
  • 2018 - 2023 To Elucidate the Regulation Mechanism of Hematopoietic Stem Cell's Mobility
  • 2015 - 2018 Blockade of PAI-1 eliminates leukemic stem cells
  • 2014 - 2016 Establishment of new method for leukemia therapy by targeting fibrinolytic pathway
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Papers (10)：
  • Abd Aziz Ibrahim, Taku Fujimura, Tomoko Uno, Tomoya Terada, Ken-ichi Hirano, Hiroyuki Hosokawa, Akio Ohta, Toshio Miyata, Kiyoshi Ando, Takashi Yahata. Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1. Frontiers in Immunology. 2024. 15
  • Kaito Harada, Takashi Yahata, Makoto Onizuka, Takamasa Ishii, Abd Aziz Ibrahim, Eri Kikkawa, Yoichi Gondo, Kiyoshi Ando. Mitochondrial Electron Transport Chain Complex II Dysfunction Causes Premature Aging of Hematopoietic Stem Cells. STEM CELLS. 2023. 41. 1. 39-49
  • Kaito Harada, Takashi Yahata, Makoto Onizuka, Abd Aziz Ibrahim, Eri Kikkawa, Toshio Miyata, Kiyoshi Ando. Plasminogen activator inhibitor type-1 is a negative regulator of hematopoietic regeneration in the adipocyte-rich bone marrow microenvironment. Biochemical and Biophysical Research Communications. 2021. 557. 180-186
  • Harama, D., Yahata, T., Kagami, K., Abe, M., Ando, N., Kasai, S., Tamai, M., Akahane, K., Inukai, T., Kiyokawa, N., et al. IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform. Cell Death Discovery. 2021. 7. 1. 139-139
  • Jin Imai, Takashi Yahata, Hitoshi Ichikawa, Abd Aziz Ibrahim, Masaki Yazawa, Hideaki Sumiyoshi, Yutaka Inagaki, Masashi Matsushima, Takayoshi Suzuki, Tetsuya Mine, et al. Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice. Intestinal Research. 2020. 18. 2. 219-228
ｍore...
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