Kiyotani Kazuma

キヨタニカズマ | Kiyotani Kazuma

Affiliation and department：

Research field (2)： Tumor diagnostics and therapeutics , Tumor biology

Research theme for competitive and other funds (13)：

2021 - 2024 遺伝子改変ネオアンチゲン特異的T細胞による泌尿器癌個別化免疫療法の開発
2021 - 2024 CDK4/6阻害剤による抗腫瘍免疫応答活性化の解析と新規多剤併用免疫療法への応用
2020 - 2023 子宮頸癌におけるWEE1阻害薬の検討およびその免疫環境の評価
2020 - 2023 新規免疫治療創出を目指したMSI-low上部消化管腺癌の網羅的免疫・ゲノム解析
2019 - 2022 Exploration of novel therapeutic targets for renal cancer by multi-omics analysis and development of treatment algorithm

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Papers (103)：

Hiroaki Hiramatsu, Rui Yokomori, Liu Shengyi, Norio Tanaka, Seiichi Mori, Kazuma Kiyotani, Osamu Gotoh, Shigeru Kusumoto, Nobuaki Nakano, Youko Suehiro, et al. Clinical landscape of TP73 structural variants in ATL patients. Leukemia. 2023
Mizuki Haraguchi, Kazuma Kiyotani, Tomohiro Tate, Seiji Sakata, Ray Sagawa, Satoshi Takagi, Satoshi Nagayama, Kengo Takeuchi, Kazuhisa Takahashi, Ryohei Katayama. Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer. Cancer immunology, immunotherapy : CII. 2023. 72. 9. 2971-2989
Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi, Satoshi Nagayama, Koji Ueda. Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations. Communications biology. 2022. 5. 1. 831-831
Kazumi Okamura, Satoshi Nagayama, Tomohiro Tate, Hiu Ting Chan, Kazuma Kiyotani, Yusuke Nakamura. Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy. Journal of Translational Medicine. 2022. 20. 1. 241-241
Kosuke Nakano, Yoko Koh, Gaku Yamamichi, Satoru Yumiba, Eisuke Tomiyama, Makoto Matsushita, Yujiro Hayashi, Cong Wang, Yu Ishizuya, Yoshiyuki Yamamoto, et al. Perioperative circulating tumor DNA enables the identification of patients with poor prognosis in upper tract urothelial carcinoma. Cancer science. 2022. 113. 5. 1830-1842

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MISC (22)：

清谷一馬. Development of neoantigen-targeted T cell therapy. 月刊腫瘍内科. 2021. 27. 5. 563-569
清谷一馬, 豊島雄二郎. 【がん治療における個別化医療の潮流】ネオ抗原を標的とした新規T細胞療法の開発. Precision Medicine. 2020. 3. 14. 1299-1302
宮内栄作, 松田達雄, Hsu Yu-Wen, 突田容子, 一ノ瀬正和, 桜田晃, 岡田克典, 齊藤涼子, 清谷一馬, 中村祐輔. EGFR遺伝子変異陽性肺腺癌におけるT細胞受容体レパトア解析(T cell receptor repertoire analysis of lung adenocarcinoma harboring EGFR mutations). 日本癌学会総会記事. 2018. 77回. 2036-2036
清谷一馬, 中村祐輔. Pharmacogenomicsに基づく乳がんホルモン療法の個別化. がん分子標的治療. 2018. 16. 2. 178-184
宮川義仁, 小松正人, 清谷一馬, 吉丸哲郎, 本田純子, 笹三徳, 三好康雄, 片桐豊雅. トリプルネガティブ乳癌における癌抑制遺伝子BCLR1の発現低下について. 日本癌学会総会記事. 2015. 74回. J-1227

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Lectures and oral presentations (73)：

腫瘍組織解析とctDNAを併用した肺癌術後のモニタリング法はMinimal residual disease検出率を向上させる
(日本呼吸器外科学会総会(Web) 2022)
SALL3のエピゲノム異常はトリプルネガティブ乳癌の薬剤抵抗性の一因となる
(日本癌学会学術総会抄録集(Web) 2021)
共通ネオアンチゲンのスクリーニング
(日本癌学会学術総会抄録集(Web) 2021)
末梢血T細胞受容体レパトア解析を用いた免疫チェックポイント阻害剤早期奏効予測バイオマーカーの開発
(日本癌学会学術総会抄録集(Web) 2021)
日本人家族性乳癌家系の新規感受性遺伝子の解析
(日本人類遺伝学会大会プログラム・抄録集 2021)

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Work history (7)：

2023/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Center for Intractable Diseases and ImmunoGenomics Project Leader
2017/01 - 現在 Japanese Foundation for Cancer Research Project for Immunogenomics, Cancer Precision Medicine Center Group Leeder
2013/04 - 2016/12 The University of Chicago, Chicago Department of Medicine Research Professional
2011/05 - 2013/03 The University of Tokushima Division of Genome Medicine, Institute for Genome Research Assistant Professor
2008/04 - 2011/04 RIKEN Laboratory for Pharmacogenetics, Center for Genomic Medicine Research Scientist

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Committee career (2)：

Awards (1)：

Association Membership(s) (3)：

米国癌学会 , 日本バイオセラピィ学会 , Japanese Cancer Association

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