2018 - 2023 Environmental electrophiles exposome and reactive sulfur species as its regulator molecule
2018 - 2020 Extracellular efflux of reactive sulfur species and its transporters
2016 - 2018 Role of reactive sulfur species as a key molecule to diminish toxicity of methylmercury in mice
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Papers (39):
Kosuke Nakamichi, Tetsuhiro Yoshino, Masahiro Akiyama, Aya Jibiki, Yuta Yokoyama, Hitoshi Kawazoe, Sayo Suzuki, Kenji Watanabe, Yun-Gi Kim, Tomonori Nakamura. Three Kampo medicines-bofutsushosan, boiogito, and daisaikoto-have different effects on host fat accumulation and the intestinal microbiota in a high-fat-diet-induced mouse model of obesity. Journal of natural medicines. 2025
Eiji Funayama, Masahiro Hosonuma, Kohei Tajima, Junya Isobe, Yuta Baba, Masakazu Murayama, Yoichiro Narikawa, Hitoshi Toyoda, Toshiaki Tsurui, Yuki Maruyama, et al. Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024. 182. 117749-117749
Yoshito Kumagai, Yumi Abiko, Masahiro Akiyama, Takamitsu Unoki, Yasuhiro Shinkai. Multi-defense pathways against electrophiles through adduct formation by low molecular weight substances with sulfur atoms. Toxicological Sciences. 2024
Kensuke Sato, Ryota Nakano, Yoshitaka Yamazaki, Hikaru Isobe, Yun-Gi Kim, Masahiro Hosonuma, Masahiro Akiyama, Yoshito Kumagai. Alteration of gene levels in fetal brain by prenatal exposure to methylmercury, copper, and their combination. Fundamental Toxicological Sciences. 2024. 11. 3. 131-139
AKIYAMA Masahiro. Gut bacteria in Toxicology. Annual Meeting of the Japanese Society of Toxicology. 2024. 51.1. Y2-4
AKIYAMA Masahiro. Adaptive cell responses to excess intracellular reactive sulfur species-induced stress. Annual Meeting of the Japanese Society of Toxicology. 2024. 51.1. S2-3
秋山雅博. Gut microbiota as a new source of supersulfides and its role. 生化学. 2024. 96. 1
仲道公輔, 地引綾, 横山雄太, 横山雄太, 河添仁, 河添仁, 鈴木小夜, 鈴木小夜, 吉野鉄大, 渡辺賢治, et al. Comparison of bofutsushosan, boiogito, and daisaikoto on inhibition of body fat accumulation and alteration of gut microbiota in mice. 腸内細菌学雑誌. 2024. 38. 2