Rchr
J-GLOBAL ID：202201007732601789
Update date: Nov. 05, 2024
Yang Zhuohao
ヨウ タクコウ | Yang Zhuohao
Affiliation and department：
Research field (3)：
Biophysics
, Cell biology
, Immunology
Research keywords (7)：
Single-cell measurement
, Fluorescence imaging
, Cell secretion
, Cell death
, Single-molecule measurement
, Ribosome
, Translation
Research theme for competitive and other funds (2)：
- 2023 - 2026 Understanding the diverse regulatory mechanisms of IL-1beta release in inflammatory responses using live-cell imaging of secretion activity
- 2015 - 2017 1分子力学測定によるSecM翻訳アレスト解除機構の解明
Papers (2)：
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Atsushi Minami, Takehito Tanzawa, Zhuohao Yang, Takashi Funatsu, Tomohisa Kuzuyama, Hideji Yoshida, Takayuki Kato, Tetsuhiro Ogawa. ‘Tuning’ of ribosome levels mediated by RNase I and hibernating ribosomes. 2024
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Zhuohao Yang, Ryo Iizuka, Takashi Funatsu. Nascent SecM chain outside the ribosome reinforces translation arrest. PloS one. 2015. 10. 3. e0122017
MISC (6)：
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高橋 悠, 寺山 由夏, 楊 倬皓, 土屋 遥香, 吉原 理紗, 田中 優実子, 山岸 舞, 白崎 善隆, 岡村 僚久, 藤尾 圭志. cell-to-cell interactionにより誘導される滑膜線維芽細胞のIL-6発現に対する1細胞イメージング. 日本臨床免疫学会総会プログラム・抄録集. 2021. 49回. 114-114
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楊 倬皓, 飯塚 怜, 郭 遠芳, 山城 竣介, 船津 高志. 新生鎖が奏でる細胞機能制御 SecMによる翻訳停止の分子メカニズム. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [3S2-5]
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Zhuohao Yang, Ryo Iizuka, Takashi Funatsu. 1P124 N-terminal region of SecM is essential for its stable translation arrest(05B. Nucleic acid : Interaction & Complex formation,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014)). Seibutsu Butsuri. 2014. 54. supplement1-2. S161-S161
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Zhuohao Yang, Ryo Iizuka, Takashi Funatsu. 3P083 Single-molecule investigation of the force required to release SecM-mediated translation arrest(01E. Protein: Measurement & Analysis,Poster). Seibutsu Butsuri. 2013. 53. supplement1-2. S225-S225
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Young Voice. Seibutsu Butsuri. 2013. 53. 6. 336-337
ｍore...
Lectures and oral presentations (6)：
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Visualization of Secretion Dynamics by Time Differentiation of Secretion Signals
(34th 2023 International Symposium on Micro-NanoMechatronics and Human Science (MHS2023) 2023)
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LIVE FLUOROSPOT: HIGH-THROUGHPUT SYSTEM FOR REAL-TIME SINGLE-CELL SECRETION IMAGING WITH OPTICAL WAVEGUIDE CHIP
(The 27th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2023) 2023)
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The real-time imaging of dynamic message-release during cell death by Live Fluorospot assay
(The 3rd Japan and Australia Meeting on Cell Death 2023 2023)
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Single-molecule force measurements of SecM translation arrest
(The 46th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2023) 2022)
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The mechanical stability of SecM translation arrest
(The 60th Annual Meeting of the Biophysical Society of Japan 2022)
ｍore...
Education (4)：
- 2014 - 2019 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Sciences
- 2012 - 2014 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Sciences
- 2010 - 2012 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences
- 2008 - 2010 The University of Tokyo College of Arts and Sciences
Professional career (1)：
- Doctor of Pharmaceutical Science (The University of Tokyo)
Work history (3)：
- 2023/08 - 現在 The University of Tokyo Research Center for Advanced Science and Technology
- 2023/04 - 現在 Japanese Foundation for Cancer Research Division of Cellular Senescence, Cancer Institute Postdoctoral Scientist
- 2019/04 - 2023/07 The University of Tokyo Graduate School of Pharmaceutical Sciences
Awards (6)：
Association Membership(s) (1)：
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