Matsuse Dai

マツセダイ | Matsuse Dai

Affiliation and department：
Research theme for competitive and other funds (15)：

2023 - 2026 ヘミチャネル阻害薬を用いたαシヌクレイン伝播阻止による多系統萎縮症の治療法開発
2023 - 2025 Elucidation of glia inflammation mechanisms common to degeneration and demyelination by novel pathogenic microglia
2022 - 2025 単一細胞RNA解析による多系統萎縮症増悪性ミクログリア亜群の同定と同細胞標的療法
2020 - 2023 A novel model of multiple sclerosis and multiple system atrophy that are differentially manifested by the time of abnormal protein expression
2020 - 2023 活性化グリア細胞制御による進行性多発性硬化症および多系統萎縮症の画期的治療法開発

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Papers (41)：

Hiroo Yamaguchi, Yuji Nishimura, Dai Matsuse, Hiroaki Sekiya, Katsuhisa Masaki, Tatsunori Tanaka, Toru Saiga, Masaya Harada, Yuu-Ichi Kira, Dennis W Dickson, et al. A rapidly progressive multiple system atrophy-cerebellar variant model presenting marked glial reactions with inflammation and spreading of α-synuclein oligomers and phosphorylated α-synuclein aggregates. Brain, behavior, and immunity. 2024. 121. 122-141
Emi Ueda, Mitsuru Watanabe, Daisuke Nakamura, Dai Matsuse, Eizo Tanaka, Kohta Fujiwara, Sawako Hashimoto, Shun Nakamura, Noriko Isobe, Koh-Hei Sonoda. Distinct retinal reflectance spectra from retinal hyperspectral imaging in Parkinson's disease. Journal of the neurological sciences. 2024. 461. 123061-123061
Yuji Nishimura, Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Tatsunori Tanaka, Eriko Matsuo, Shotaro Hayashida, Mitsuru Watanabe, Takuya Matsushita, Shoko Sadashima, et al. Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy. Brain pathology (Zurich, Switzerland). 2023. 33. 3. e13131
Jun Mitsui, Takashi Matsukawa, Yukari Uemura, Takuya Kawahara, Ayaka Chikada, Kristine Joyce L Porto, Hiroya Naruse, Masaki Tanaka, Hiroyuki Ishiura, Tatsushi Toda, et al. High-dose ubiquinol supplementation in multiple-system atrophy: a multicentre, randomised, double-blinded, placebo-controlled phase 2 trial. EClinicalMedicine. 2023. 59. 101920-101920
Yu Hashimoto, Ryo Yamasaki, Senri Ko, Eriko Matsuo, Yuko Kobayakawa, Katsuhisa Masaki, Dai Matsuse, Noriko Isobe. Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation. International journal of molecular sciences. 2022. 23. 24

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MISC (3)：

松瀬大. 進行性核上性麻痺. 2022
松瀨大, 吉良潤一. 多発性硬化症・視神経脊髄炎. 2014
松瀨大, 吉良潤一. 多発性硬化症. 2013

Lectures and oral presentations (110)：

新規小脳型多系統萎縮症モデルのCSF-1R阻害剤治療
(第15回パーキンソン病・運動障害疾患コングレス 2021)
パーキンソン病の病態と治療
(大塚製薬株式会社社内講演 2021)
Early decrease of peripheral blood intermediate monocytes in multiple system atrophy cerebellar-type.
(62nd Annual Meeting of the Japanese Society of Neurology 2021)
サフィナミド100mg投与意義~当院での使用経験も踏まえて~
(PD診療WEBセミナー ~サフィナミド発売2周年を迎えて~ 2022)
難病ネットワークの紹介
(第2回福岡県難病診療連携拠点病院研修会 2022)

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Committee career (36)：

2022/04 - 2024/03 九州大学自己点検・評価委員
2019/11 - 2024/03 日本難病ネットワーク学会評議員
2022/02 - 2022/05 九州大学病棟医長
2022/02 - 2022/05 九州大学感染対策委員
2022/02 - 2022/05 九州大学入院診療部門運営委員

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Association Membership(s) (5)：

日本再生医療学会 , 日本神経免疫学会 , 日本神経学会 , 日本末梢神経学会 , 日本内科学会

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