Takeo Makoto

タケオマコト | Takeo Makoto

Affiliation and department：
Job title： Associate professor
Homepage URL (1)： https://www.aikosada.com/

Research field (2)： Cell biology , Developmental biology

Research keywords (4)： Cell dynamics , Stem cell , Regeneration , organogenesis

Research theme for competitive and other funds (12)：

2022 - 2025 keloidal spheroidとシュワン細胞からなるケロイドモデルの作成
2022 - 2024 Identification of new mechanism of morphological rhythm generated by niche switching
2021 - 2024 三次元器官の生体外構築を目指した哺乳類成体器官における形態形成メカニズムの解明
2019 - 2022 Development of innovative technologies towered organ regeneration by control of organ fate
2018 - 2021 Identification of organ-inductive potential nail mesenchymal cell and development of fundamental method for nail organ regeneration

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Papers (41)：

Atsuko Ota, Hiroaki Kitamura, Keigo Sugimoto, Miho Ogawa, Naoshi Dohmae, Hiroki Okuno, Kazuya Takahashi, Kazutaka Ikeda, Tsutomu Tomita, Naoki Matsuoka, et al. Comparative studies of hair shaft components between healthy and diseased donors. PloS one. 2024. 19. 5. e0301092
Makoto Takeo, Koh-Ei Toyoshima, Riho Fujimoto, Tomoyo Iga, Miki Takase, Miho Ogawa, Takashi Tsuji. Cyclical dermal micro-niche switching governs the morphological infradian rhythm of mouse zigzag hair. Nature communications. 2023. 14. 1. 4478-4478
Qi Sun, Wendy Lee, Hai Hu, Tatsuya Ogawa, Sophie De Leon, Ioanna Katehis, Chae Ho Lim, Makoto Takeo, Michael Cammer, M. Mark Taketo, et al. Dedifferentiation maintains melanocyte stem cells in a dynamic niche. Nature. 2023
Jun Ishikawa, Makoto Takeo, Ayako Iwadate, Junko Koya, Miho Kihira, Masamitsu Oshima, Yuki Suzuki, Kazushi Taniguchi, Ayaka Kobayashi, Takashi Tsuji. Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration. Communications biology. 2021. 4. 1. 409-409
Makoto Takeo, Kyosuke Asakawa, Koh-Ei Toyoshima, Miho Ogawa, JingJing Tong, Tarou Irié, Masayuki Yanagisawa, Akio Sato, Takashi Tsuji. Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration. Scientific reports. 2021. 11. 1. 1173-1173

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MISC (6)：

武尾真, 辻孝. 男性型・女性型脱毛症の治療とケア-現状と未来-III-3 再生医療周期的な毛包を再生させる幹細胞の増幅と特定. 美容皮膚医学Beauty. 2022. 5. 3
Development of regenerative skin organ system with skin appendages. コスメトロジー研究報告. 2021. 29. 135-140
小川美帆, 武尾真, 岡本尚一, 辻孝. 毛髪を"種"から再生する未来の再生医療. 現代化学. 2019. 577. 26-29
Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Induces Pigmented Hair Regeneration. 細胞工学. 2013. 32. 4. 430-434
武尾真. いきものの不思議ヤマトヒメミミズ--小さな体にひそむ多くの不思議. 生物の科学遺伝. 2009. 63. 1. 8-11

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Patents (1)：

Education (3)：

Work history (4)：

2024/01 - 現在 Kyushu University Medical Institute of Bioregulation Department of Molecular and Cellular Biology
2019/12 - 2023/12 RIKEN
2016/04 - 2018/11 RIKEN
2008/12 - 2016/03 New York University School of Medicine The Ronald O. Perelman Department of Dermatology

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