Miyauchi Eiji

ミヤウチエイジ | Miyauchi Eiji

Affiliation and department：

Research keywords (4)：自己免疫疾患 , 粘膜免疫 , 食品科学 , 腸内細菌

Research theme for competitive and other funds (24)：

2023 - 2028 Enhancing wellbeing through human-dog symbiosis - links with physical, prosocial and social network development.
2024 - 2027 Establishment of personalized medicine and prevention methods for colorectal cancer considering the intestinal environment
2024 - 2027 母体炎症が次世代の自己免疫疾患病態に及ぼす影響解明と食品成分による抑制への展開
2024 - 2026 歯周炎が惹起するInflammagingにおける口腸連関機構の解明
2023 - 2026 母体炎症が次世代の 1 型糖尿病病態に与える影響

2023 - 2025 母体炎症による仔の自己免疫疾患リスク増加機序の解析

2022 - 2025 食物繊維による中枢神経系炎症の制御

2022 - 2025 宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究

2023 - 2024 自己免疫性脳脊髄炎の制御に関わる腸内代謝産物の解明

2023 - 2024 食餌因子による腸内環境変動を介した自己免疫疾患制御

2021 - 2023 腸内細菌叢による中枢神経系の制御

2022 - 2023 腸内代謝産物を介した多発性硬化症制御機構の解明

2019 - 2023 腸内細菌制御による多発性硬化症治療効果の解析

2019 - 2023 Human health promotion by inter-species symbiosis-Mental and physical health development of children by human-dog coexistent of microbiota

2019 - 2022 The impact of gut microbiota on autoimmune diseases

2018 - 2022 The study for the developmental mechanism of sociality which is specific to mammalian species

2016 - 2019 Identification of human-derived gut microbes involved in the inflammation in the central nerve system

2016 - 2019 Comprehensive analysis of intestinal colonization factors derived from gut microbes

2015 - 2019 Brain-gut axis mechanisms formed by mother-pup interactions for the resilience to stress

2015 - 2018 Analyses of interaction between malaria and intestinal microbiota in patients in Uganda

2014 - 2016 Mechanisms of effects of gut microbiota on inflammation in the central nerve system

2013 - 2016 ビフィズス菌による腸管上皮-T細胞間相互作用の制御に基づく腸炎抑制機構の解明

2012 - 2014 ビフィズス菌による腸管上皮-T細胞間相互作用の制御に基づく腸炎抑制機構の解明

2009 - 2011 乳酸菌による腸管バリア機能保護メカニズムの解明とそれを意図する機能性食品の創製

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Papers (29)：

Alex Steimle, Mareike Neumann, Erica T. Grant, Stéphanie Willieme, Alessandro De Sciscio, Amy Parrish, Markus Ollert, Eiji Miyauchi, Tomoyoshi Soga, Shinji Fukuda, et al. Gut microbial factors predict disease severity in a mouse model of multiple sclerosis. Nature Microbiology. 2024
Itsuka Kamimura, Eiji Miyauchi, Tadashi Takeuchi, Noriaki Tsuchiya, Kanami Tamura, Ayumi Uesugi, Hiroki Negishi, Takashi Taida, Tamotsu Kato, Masami Kawasumi, et al. Modulation of gut microbiota composition due to early weaning stress induces depressive behavior during the juvenile period in mice. Animal Microbiome. 2024. 6. 1
Tomoya Tsukimi, Nozomu Obana, Suguru Shigemori, Kazuharu Arakawa, Eiji Miyauchi, Jiayue Yang, Isaiah Song, Yujin Ashino, Masataka Wakayama, Tomoyoshi Soga, et al. Genetic mutation in Escherichia coli genome during adaptation to the murine intestine is optimized for the host diet. mSystems. 2024. 9. 2
Tadashi Takeuchi, Keishi Kameyama, Eiji Miyauchi, Yumiko Nakanishi, Takashi Kanaya, Takayoshi Fujii, Tamotsu Kato, Takaharu Sasaki, Naoko Tachibana, Hiroki Negishi, et al. Fatty acid overproduction by gut commensal microbiota exacerbates obesity. Cell metabolism. 2023. 35. 2. 361-375
Eiji Miyauchi, Chikako Shimokawa, Alex Steimle, Mahesh S Desai, Hiroshi Ohno. The impact of the gut microbiome on extra-intestinal autoimmune diseases. Nature reviews. Immunology. 2022

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MISC (17)：

内田真太郎, 宮内栄治. 腸管粘膜付着細菌叢の解析法. 臨床免疫・アレルギー科. 2024. 81. 1. 77-83
宮内栄治, 佐々木伸雄. 腸内代謝物質を介した免疫系の修飾. 生化学. 2023. 95. 4. 475-482
宮内栄治, 大野博司. 多発性硬化症の発症における腸内細菌の役割. 感染・炎症・免疫. 2022. 52. 1
宮内栄治, 大野博司. Multiple sclerosis and small intestinal microbiota. 月刊臨床免疫・アレルギー科. 2021. 75. 1
宮内栄治. Regulation of inflammatory responses in the central nervous system by gut microbiota. 腸内細菌学雑誌. 2021. 35. 2

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Association Membership(s) (3)：

農芸化学会 , 分子生物学会 , 日本免疫学会

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