Rchr
J-GLOBAL ID：202201020186210516   Update date: May. 28, 2026

Hatazawa Suguru

ハタザワ スグル | Hatazawa Suguru
Affiliation and department：
The University of Tokyo Institute for Quantitative Biosciences

About The University of Tokyo Institute for Quantitative Biosciences


Job title： Assistant professor
Research field  (2)： Structural biochemistry ,  Molecular biology
Research keywords  (3)： クライオ電子顕微鏡 ,  クロマチン ,  エピジェネティクス
Research theme for competitive and other funds  (2)：
  • 2025 - 2027 ヒストンアセチル化酵素p300の転写因子と協調したヌクレオソーム結合様式の網羅的解析
  • 2023 - 2025 p300によるヒストンアセチル化伝搬機構の構造生物学的解析
Papers (11)：
  • Suguru Hatazawa, Yoshimasa Takizawa, Hitoshi Kurumizaka. Preparation of Chromatin Fragments From Human Cells for Cryo-EM Analysis. BIO-PROTOCOL. 2025. 15. 1382
  • Takuro Shioi, Suguru Hatazawa, Yoshimasa Takizawa, Hitoshi Kurumizaka. Mechanistic insights into RAD51-mediated nucleosome binding and remodeling in homologous recombination. DNA Repair. 2025. 103891-103891
  • Suguru Hatazawa, Naoki Horikoshi, Hitoshi Kurumizaka. Structural diversity of noncanonical nucleosomes: Functions in chromatin. Current Opinion in Structural Biology. 2025. 92. 103054-103054
  • Suguru Hatazawa, Yoshiyuki Fukuda, Yuki Kobayashi, Lumi Negishi, Masahide Kikkawa, Yoshimasa Takizawa, Hitoshi Kurumizaka. Cryo-EM Structures of Native Chromatin Units From Human Cells. Genes to Cells. 2025. 30. 3
  • Akihisa Osakabe, Yoshimasa Takizawa, Naoki Horikoshi, Suguru Hatazawa, Lumi Negishi, Shoko Sato, Frédéric Berger, Tetsuji Kakutani, Hitoshi Kurumizaka. Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. Nature communications. 2024. 15. 1. 5187-5187
ｍore...
Books (3)：
  • Journal of Japanese Biochemical Society 96(6), Molecular mechanism of RAD51-mediated homologous recombi- nation initiation on chromatin
    2024
  • Cryo-EM structures of RAD51 bound to a nucleosome with a double DNA strand break
    2024 ISBN:9784758125833
  • Mechanism of the nucleosome transcription regulated by the elongation factors and the histone chaperone FACT
    2023
Lectures and oral presentations  (22)：
  • Structural and functional analyses of histone acetyltransferase p300 on acetylated nucleosomes
    (Pacifichem 2025 2025)
  • Structural and functional characterization of histone acetyltransferase p300 bound to acetylated nucleosomes
    (2025)
  • Cryo-EM analysis of chromatin extracted from human cells
    (2025)
  • Cryo-FIB-SEMを用いた精子核内のゲノムDNA収納様式の解明
    (学術変革領域研究(A) 個体の細胞運命決定を担うクロマチンのエピコードの解読 第二回領域班会議 2025)
  • Structural and functional insights into histone acetylation by p300 bound to the nucleosome
    (2025)
ｍore...
Professional career (1)：
  • Doctor of Philosophy (The University of Tokyo)
Work history (3)：
  • 2025/04 - 現在 The University of Tokyo Institute for Quantitative Biosciences Assistant professor
  • 2023/09 - 現在 Saitama University
  • 2022/07 - 2025/03 The University of Tokyo Institute for Quantitative Biosciences Project Researcher
Awards (8)：
  • 2025/06 - 学術変革領域研究(A)「細胞運命コード」第二回領域会議 ベストポスター賞
  • 2024/07 - 学術変革領域研究(A)「細胞運命コード」第一回領域会議 ポスター発表 優秀発表賞
  • 2023/10 - JB論文賞 Structural and biochemical analyses of the nucleosome containing Komagataella pastoris histones
  • 2022/10 - 優秀口頭発表賞 Nucleosome binding modes of histone acetyltransferase p300
  • 2022/10 - 優秀ポスター発表賞 Nucleosome binding modes of histone acetyltransferase p300
Show all
Association Membership(s) (4)：
The Japanese Society for Epigenetics ,  The Japanese Biochemical Society ,  The Molecular Biology Society of Japan ,  The Genetics Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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