Rchr
J-GLOBAL ID:202201020765860387   Update date: Feb. 01, 2024

Mutoh Hiroki

ムトウ ヒロキ | Mutoh Hiroki
Affiliation and department:
Job title: Assistant Professor
Research field  (2): Neuroscience - general ,  Physiology
Research keywords  (2): 電気生理学 パッチクランプ ,  脳波測定(EEG)
Research theme for competitive and other funds  (11):
  • 2020 - 2023 Elucidation of neurodevelopmental disorder caused by CaMK2 mutant mice
  • 2017 - 2021 Functional analysis of arcuate nucleus astrocytes with feeding disorders
  • 2016 - 2021 Cell and Molecular mechanisms underlying the interaction between the innate immune system and metabolism in lysosomes
  • 2015 - 2020 Understanding human nature based on non-linear neuronal oscillation
  • 2015 - 2020 Modal shifts in cellular and network oscillations
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Papers (42):
  • Md Monirul Islam, Hiroki Mutoh, Kazushi Aoto, Hazrat Belal, Hirotomo Saitsu. Cnpy32xHA mice reveal neuronal expression of Cnpy3 in the brain. Journal of neuroscience methods. 2022. 383. 109730-109730
  • Kazushi Aoto, Shuji Takabayashi, Hiroki Mutoh, Hirotomo Saitsu. Generation of Flag/DYKDDDDK Epitope Tag Knock-In Mice Using i-GONAD Enables Detection of Endogenous CaMKIIα and β Proteins. International journal of molecular sciences. 2022. 23. 19
  • Hiroki Mutoh, Kazushi Aoto, Takehiro Miyazaki, Atsuo Fukuda, Hirotomo Saitsu. Elucidation of pathological mechanism caused by human disease mutation in CaMKIIβ. Journal of neuroscience research. 2022. 100. 3. 880-896
  • Sachiko Miyamoto, Mitsuhiro Kato, Kenji Sugiyama, Ryo Horiguchi, Mitsuko Nakashima, Kazushi Aoto, Hiroki Mutoh, Hirotomo Saitsu. A boy with biallelic frameshift variants in TTC5 and brain malformation resembling tubulinopathies. Journal of Human Genetics. 2021. 66. 12. 1189-1192
  • Kazushi Aoto, Mitsuhiro Kato, Tenpei Akita, Mitsuko Nakashima, Hiroki Mutoh, Noriyuki Akasaka, Jun Tohyama, Yoshiko Nomura, Kyoko Hoshino, Yasuhiko Ago, et al. ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice. Nature Communications. 2021. 12. 1
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MISC (32):
  • 青戸一司, 高林秀次, 武藤弘樹, 才津浩智. 簡便なi-GONAD法によるFlag(DYKDDDDK)タグを挿入したマウスの作製とその有用性. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
  • 才津浩智, 武藤弘樹, 青戸一司, 宮嵜岳大, 宮嵜岳大, 福田敦夫. ヒト変異ノックインマウスを用いたCaMKIIβ変異の病態解明. 日本遺伝子診療学会大会プログラム・抄録集. 2022. 29th
  • 宮本祥子, 加藤光広, 杉山謙二, 堀口涼, 青戸一司, 武藤弘樹, 中島光子, 才津浩智. Tubulinopathiesに似たMRI所見を認めたTTC5症例. 日本人類遺伝学会大会プログラム・抄録集. 2021. 66th (CD-ROM)
  • SINHA Adya Saran, WANG Tianying, MUTOH Hiroki, AKITA Tenpei, YANAGAWA Yuchio, KAWAI Tomoko, HATA Kenichiro, FUKUDA Atsuo. Gad1 heterozygotes subjected to prenatal stress undergo epigenetic dysregulation of genes perturbing neurodevelopment and behavior. 日本生理学雑誌(Web). 2021. 83. 2
  • 才津浩智, 青戸一司, 加藤光広, 秋田天平, 中島光子, 武藤弘樹, 赤坂紀幸, 遠山潤, 野村芳子, 星野恭子, et al. 液胞(H+)-ATPアーゼのサブユニットをコードするATP6V0A1は,ヒトとマウスの脳の発達に不可欠である. 日本先天異常学会学術集会プログラム・抄録集. 2021. 61st (CD-ROM)
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Books (9):
  • Optical probes in biology
    CRC Press 2017 ISBN:9781138199934
  • Optical Imaging of Neocortical Dynamics.
    Springer 2014 ISBN:9781627037853
  • in vivo実験医学によるヒト疾患解明の最前線 : 生体イメージングとモデル動物を用いた研究戦略と臨床応用
    羊土社 2012 ISBN:9784758103206
  • Optogenetics : tools for controlling and monitoring neuronal activity
    Elsevier 2012 ISBN:9780444594266
  • BIOINDUSTRY
    2011
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Professional career (1):
  • 博士(医学) (浜松医科大学)
Work history (3):
  • 2018/04 - 現在 浜松医科大学 医学部 医化学講座 助教
  • 2013/04 - 2018/03 浜松医科大学 医学部 神経生理学講座 助教
  • 2002/04 - 2013/03 RIKEN Brain Science Institute Laboratory for Neuronal Circuit Dynamics
Association Membership(s) (2):
日本神経科学学会 ,  日本生理学会
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