Art

J-GLOBAL ID：202202217217559031   Reference number：22A2072265

Immunoproteasome Function in Normal and Malignant Hematopoiesis

正常および悪性造血における免疫プロテアソーム機能【JST・京大機械翻訳】

Author (5)： Tubio-Santamaria Nuria (Innere Medicine C, Universitaetsmedizin Greifswald, 17475 Greifswald, Germany) ,  Ebstein Frederic (Institut fuer Biochemie und Molekularbiologie, Universitaetsmedizin Greifswald, 17475 Greifswald, Germany) ,  Heidel Florian H. (Innere Medicine C, Universitaetsmedizin Greifswald, 17475 Greifswald, Germany) ,  Heidel Florian H. (Leibniz Institute on Aging, Fritz Lipmann-Institute, 07745 Jena, Germany) ,  Krueger Elke (Institut fuer Biochemie und Molekularbiologie, Universitaetsmedizin Greifswald, 17475 Greifswald, Germany)
Material： Cells (Web)
Volume： 10  Issue： 7  Page： 1577  Publication year： 2021 
JST Material Number： U7155A  ISSN： 2073-4409  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The ubiquitin-proteasome syste...

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Thesaurus term： inflammation ,  antitumor drug ,  cell ,  side effect ,  *immunity ,  drug resistance ,  *hemopoiesis ,  clinical trial ,  homeostasis ,  proteinase inhibitor ,  ubiquitin ,  multiple myeloma ,  autoimmune disease ,  *proteasome ,  molecular targeting drug
Semi thesaurus term： 悪性腫瘍 ,  プロテアソーム阻害剤 ,  *免疫プロテアソーム , 【Automatic Indexing@JST】

Author keywords (5)： ubiquitin-proteasome system (UPS) ,  immunoproteasome (iP) ,  proteasome inhibitors (PIs) ,  hematopoiesis ,  hematologic malignancies

JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Cell physiology in general  (EF02010S)

Reference (193)：

• Glickman, M.H.; Ciechanover, A. The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction. Physiol. Rev. 2002, 82, 373-428.
• Pickart, C.M.; Eddins, M.J. Ubiquitin: Structures, functions, mechanisms. Biochim. Biophys. Acta 2004, 1695, 55-72.
• Ardley, H.C.; Robinson, P.A. E3 ubiquitin ligases. Essays Biochem. 2005, 41, 15-30.
• Sadowski, M.; Suryadinata, R.; Tan, A.R.; Roesley, S.N.A.; Sarcevic, B. Protein Monoubiquitination and Polyubiquitination Generate Structural Diversity to Control Distinct Biological Processes. IUBMB Life 2012, 64, 136-142.
• Baumeister, W.; Walz, J.; Zuhl, F.; Seemüller, E. The proteasome: Paradigm of a self-compartmentalizing protease. Cell 1998, 92, 367-380.

Terms in the title (2)： 造血 ,  免疫プロテアソーム