Art

J-GLOBAL ID：202202226420887185   Reference number：22A1025076

DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer

DNAメチル化:胃癌に対する重要なバイオマーカーと治療標的【JST・京大機械翻訳】

Author (8)： Zeng Yunqing (1Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Rong Huimin (2Department of Reconstructive Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Xu Jianwei (3Department of Pancreatic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Cao Ruyue (1Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Li Shuhua (1Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Gao Yanjing (1Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Cheng Baoquan (1Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Zhou Tao (4Department of Geriatric Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China)
Material： Frontiers in Genetics (Web)
Volume： 13  Page： 823905  Publication year： 2022 
JST Material Number： U7071A  ISSN： 1664-8021  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Gastric cancer (GC) is a very ...

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Thesaurus term： *methylation ,  *tumor ,  human(primates) ,  prognosis ,  tumor marker ,  *stomach tumor ,  *biomarker
Semi thesaurus term： *DNAメチル化 ,  悪性腫瘍 ,  予後不良 ,  健康問題 ,  *治療標的 , 【Automatic Indexing@JST】

Author keywords (5)： DNA methylation ,  gastric cancer ,  diagnosis ,  therapy ,  prognosis

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (121)：

• AbbaszadeganM. R., MoavenO., SimaH. R., GhafarzadeganK., A'RabiA., ForghaniM. N., et al (2008). P16 Promoter Hypermethylation: A Useful Serum Marker for Early Detection of Gastric Cancer. World J. Gastroenterol. 14 (13), 2055-2060. doi: 10.3748/wjg.14.2055
• AlarcónM. A., OlivaresW., Córdova-DelgadoM., Muñoz-MedelM., de MayoT., Carrasco-AviñoG., et al (2020). The Reprimo-like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-invasive Detection of Gastric Cancer. Int. J. Mol. Sci. 21 (24). doi: 10.3390/ijms21249472
• AnN., YuZ., HeX. J., ZhaoY. Y., YuL., ZhangY. C., et al (2020). Promoter Methylation of DNA Repair Genes Predicts Disease-free Survival of Gastric Adenocarcinoma after Adjuvant Radiotherapy. Mol. Ther. Oncolytics 18, 109-117. doi: 10.1016/j.omto.2020.06.006
• BalgkouranidouI., KarayiannakisA., MatthaiosD., BolanakiH., TripsianisG., TentesA. A., et al (2013). Assessment of SOX17 DNA Methylation in Cell Free DNA from Patients with Operable Gastric Cancer. Association with Prognostic Variables and Survival. Clin. Chem. Lab. Med. 51(7), 1505-1510. doi: 10.1515/cclm-2012-0320
• BalgkouranidouI., MatthaiosD., KarayiannakisA., BolanakiH., MichailidisP., XenidisN., et al (2015). Prognostic Role of APC and RASSF1A Promoter Methylation Status in Cell Free Circulating DNA of Operable Gastric Cancer Patients. Mutat. Research/Fundamental Mol. Mech. Mutagenesis 778, 46-51. doi: 10.1016/j.mrfmmm.2015.05.002

Terms in the title (4)： DNAメチル化 ,  胃癌 ,  バイオマーカー ,  治療標的