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J-GLOBAL ID：202202228698608718   Reference number：22A1176052

Mitochondrial Transplantation Attenuates Neural Damage and Improves Locomotor Function After Traumatic Spinal Cord Injury in Rats

ミトコンドリア移植はラットにおける外傷性脊髄損傷後の神経損傷を軽減し運動機能を改善する【JST・京大機械翻訳】

Author (16)： Lin Ming-Wei (Department of Medical Research, E-Da Hospital, E-Da Cancer Hospital, Kaohsiung City, Taiwan) ,  Lin Ming-Wei (Department of Nursing, College of Medicine, I-Shou University, Kaohsiung City, Taiwan) ,  Lin Ming-Wei (Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung City, Taiwan) ,  Fang Shih-Yuan (Department of Anesthesiology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan City, Taiwan) ,  Hsu Jung-Yu C. (Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan City, Taiwan) ,  Hsu Jung-Yu C. (Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan) ,  Huang Chih-Yuan (Section of Neurosurgery, Department of Surgery, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan City, Taiwan) ,  Lee Po-Hsuan (Section of Neurosurgery, Department of Surgery, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan City, Taiwan) ,  Huang Chi-Chen (Section of Neurosurgery, Department of Surgery, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan City, Taiwan) ,  Chen Hui-Fang (Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan City, Taiwan) ,  Lam Chen-Fuh (Department of Medical Research, E-Da Hospital, E-Da Cancer Hospital, Kaohsiung City, Taiwan) ,  Lam Chen-Fuh (Department of Anesthesiology, E-Da Hospital, E-Da Cancer Hospital, Kaohsiung City, Taiwan) ,  Lam Chen-Fuh (College of Medicine, I-Shou University, Kaohsiung City, Taiwan) ,  Lee Jung-Shun (Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan City, Taiwan) ,  Lee Jung-Shun (Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan) ,  Lee Jung-Shun (Section of Neurosurgery, Department of Surgery, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan City, Taiwan)
Material： Frontiers in Neuroscience (Web)
Volume： 16  Page： 800883  Publication year： 2022 
JST Material Number： U7087A  ISSN： 1662-453X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Mitochondrial dysfunction is a...

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Thesaurus term： fluorescence ,  *spinal cord ,  *mitochondria ,  *rat ,  *injury ,  dysfunction ,  aneurysm ,  *transplantation ,  *spinal cord injury ,  apoptosis ,  cell death ,  Paralichthys olivaceus ,  oxidative stress ,  mitochondrial disease
Semi thesaurus term： *運動機能 ,  炎症反応 ,  神経細胞死 ,  ミトコンドリア機能障害 , 【Automatic Indexing@JST】

Author keywords (5)： allogenic mitochondria ,  mitochondrial dysfunction ,  mitochondrial transplantation ,  oxidative stress ,  spinal cord injury

JST classification (1)： Basic neurology  (GN01020W)

Reference (62)：

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• Al Amir Dache Z., Otandault A., Tanos R., Pastor B., Meddeb R., Sanchez C., et al (2020). Blood contains circulating cell-free respiratory competent mitochondria. FASEB J. 34 3616-3630. doi: 10.1096/fj.201901917RR
• Bains M., Hall E. D. (2012). Antioxidant therapies in traumatic brain and spinal cord injury. Biochim. Biophys. Acta 1822 675-684. doi: 10.1016/j.bbadis.2011.10.017
• Bause A. S., Haigis M. C. (2013). SIRT3 regulation of mitochondrial oxidative stress. Exp. Gerontol. 48 634-639. doi: 10.1016/j.exger.2012.08.007
• Beattie M. S., Farooqui A. A., Bresnahan J. C. (2000). Review of current evidence for apoptosis after spinal cord injury. J. Neurotrauma 17 915-925. doi: 10.1089/neu.2000.17.915

Terms in the title (6)： ミトコンドリア ,  移植 ,  ラット ,  外傷性脊髄損傷 ,  神経損傷 ,  運動機能