Art

J-GLOBAL ID：202202229999826153   Reference number：22A1019393

The Molecular Basis of Spinocerebellar Ataxia Type 7

脊髄小脳失調症7型の分子基盤【JST・京大機械翻訳】

Author (13)： Goswami Rituparna (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Bello Abudu I. (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Bean Joe (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Costanzo Kara M. (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Omer Bwaar (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Cornelio-Parra Dayanne (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Odah Revan (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Ahluwalia Amit (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Allan Shefaa K. (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Nguyen Nghi (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Shores Taylor (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States) ,  Aziz N. Ahmad (Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany) ,  Mohan Ryan D. (Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO, United States)
Material： Frontiers in Neuroscience (Web)
Volume： 16  Page： 818757  Publication year： 2022 
JST Material Number： U7087A  ISSN： 1662-453X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Spinocerebellar ataxia (SCA) t...

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Thesaurus term： gene ,  *spinal cord ,  protein ,  phenotype ,  subunit ,  complex(substance) ,  polyamino acid ,  acetyltransferase ,  characterization ,  repetitive sequence ,  pathogenesis ,  microsatellite
Semi thesaurus term： *脊髄小脳失調 ,  トリヌクレオチド反復 ,  アミノ末端 ,  ポリグルタミン ,  クロマチン修飾 , 【Automatic Indexing@JST】

Author keywords (5)： ATXN7 ,  USP22 ,  SAGA complex ,  polyglutamine expansion ,  deubiquitination

JST classification (3)： Genetic variation  (EC01030Y) ,  Nervous system diseases  (GN03000O) ,  Biological function  (EB03040U)

Reference (141)：

• Ahmad S. I. (2012). Neurodegenerative Diseases. New York: Springer-Verlag.
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• Ansorge O., Giunti P., Michalik A., Van Broeckhoven C., Harding B., Wood N., et al (2004). Ataxin-7 aggregation and ubiquitination in infantile SCA7 with 180 CAG repeats. Ann. Neurol. 56 448-452. doi: 10.1002/ana.20230
• Arnoriaga Rodríguez M., Blasco G., Coll C., Biarnés C., Contreras-Rodríguez O., Garre-Olmo J., et al (2019). Glycated Hemoglobin, but not Insulin Sensitivity, is Associated with Memory in Subjects with Obesity. Obesity 27 932-942. doi: 10.1002/oby.22457
• Arrasate M., Mitra S., Schweitzer E. S., Segal M. R., Finkbeiner S. (2004). Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 431 805-810. doi: 10.1038/nature02998

Terms in the title (3)： 脊髄小脳失調症 ,  分子 ,  基盤