Art

J-GLOBAL ID：202202239410316752   Reference number：22A0302282

Associations of Serum Uromodulin and Its Genetic Variants With Blood Pressure and Hypertension in Chinese Adults

中国人成人における血清ウロモジュリンおよびその遺伝的変異と血圧および高血圧との関連【JST・京大機械翻訳】

Author (39)： Wang Yang (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Wang Yang (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Du Ming-Fei (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Yao Shi (Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China) ,  Zou Ting (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Zhang Xiao-Yu (Department of Cardiology, Northwest Women’s and Children’s Hospital of Xi’an Jiaotong University Health Science Center, Xi’an, China) ,  Hu Gui-Lin (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Chu Chao (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Chu Chao (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Liao Yue-Yuan (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Liao Yue-Yuan (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Chen Chen (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Wang Dan (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Wang Dan (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Ma Qiong (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Ma Qiong (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Wang Ke-Ke (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Wang Ke-Ke (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Sun Yue (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Sun Yue (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Niu Ze-Jiaxin (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Niu Ze-Jiaxin (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Yan Rui-Chen (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Yan Rui-Chen (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Yan Yu (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Yan Yu (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China) ,  Zhou Hao-Wei (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Jia Hao (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Gao Wei-Hua (Department of Cardiology, Xi’an No.1 Hospital, Xi’an, China) ,  Li Hao (Department of Critical Care Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Li Chun-Hua (Department of Ophthalmology, Xi’an People’s Hospital, Xi’an, China) ,  Chen Fang-Yao (Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, China) ,  Gao Ke (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Zhang Jie (Department of Cardiology, Xi’an People’s Hospital, Xi’an, China) ,  Safirstein Robert (Department of Medicine, Yale University School of Medicine, New Haven, CT, United States) ,  Wang Feng (Department of Nephrology, Jiangsu University Affiliated Shanghai Eighth People’s Hospital, Shanghai, China) ,  Yang Tie-Lin (Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China) ,  Mu Jian-Jun (Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China) ,  Mu Jian-Jun (Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an, China)
Material： Frontiers in Cardiovascular Medicine (Web)
Volume： 8  Page： 710023  Publication year： 2021 
JST Material Number： U7061A  ISSN： 2297-055X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Background: Uromodulin, also n...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=22A0302282&from=J-GLOBAL&jstjournalNo=U7061A") }}

Thesaurus term： concentration(ratio) ,  risk ,  sodium ,  *blood pressure ,  gene ,  *serum ,  *hypertension ,  protein ,  mutant ,  homeostasis ,  population(statistics) ,  puberty(human) ,  genetic polymorphism
Semi thesaurus term： 被験者 ,  *ウロモジュリン , 【Automatic Indexing@JST】

Author keywords (5)： gene polymorphism ,  hypertension ,  uromodulin (UMOD) ,  longitudinal change ,  blood pressure

JST classification (3)： Urogenital diseases  (GM03000L) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Molecular genetics in general  (EC02010J)

Reference (47)：

• Lu J, Lu Y, Wang X, Li X, Linderman GC, Wu C, et al. Prevalence, awareness, treatment, and control of hypertension in China: data from 17 million adults in a population-based screening study (China PEACE Million Persons Project). Lancet. (2017) 390:2549-58. doi: 10.1016/S0140-6736(17)32478-9
• Beaney T, Burrell LM, Castillo RR, Charchar FJ, Cro S, Damasceno A, et al. May measurement month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension. Eur Heart J. (2019) 40:2006-17. doi: 10.1093/eurheartj/ehz300
• Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. (2002) 360:1903-13. doi: 10.1016/S0140-6736(02)11911-8
• Meneton P, Jeunemaitre X, de Wardener HE, MacGregor GA. Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases. Physiol Rev. (2005) 85:679-715. doi: 10.1152/physrev.00056.2003
• Frame AA, Wainford RD. Mechanisms of altered renal sodium handling in age-related hypertension. Am J Physiol Renal Physiol. (2018) 315:F1-6. doi: 10.1152/ajprenal.00594.2017

Terms in the title (7)： 中国人 ,  成人 ,  血清 ,  ウロモジュリン ,  遺伝的変異 ,  血圧 ,  高血圧