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J-GLOBAL ID：202202241867305905   Reference number：22A1020520

Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies

COVID-19治療改善のための薬理遺伝学と精密医療アプローチ【JST・京大機械翻訳】

Author (15)： Biswas Mohitosh (1Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ,  Biswas Mohitosh (2Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand) ,  Biswas Mohitosh (3Department of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh) ,  Sawajan Nares (1Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ,  Sawajan Nares (2Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand) ,  Sawajan Nares (4Department of Pathology, School of Medicine, Mae Fah Luang University, Chiang Rai, Thailand) ,  Rungrotmongkol Thanyada (5Structural and Computational Biology Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand) ,  Rungrotmongkol Thanyada (6Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok, Thailand) ,  Sanachai Kamonpan (5Structural and Computational Biology Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand) ,  Ershadian Maliheh (1Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ,  Ershadian Maliheh (2Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand) ,  Sukasem Chonlaphat (1Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ,  Sukasem Chonlaphat (2Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand) ,  Sukasem Chonlaphat (7Pharmacogenomics and Precision Medicine, The Preventive Genomics and Family Check-up Services Center, Bumrungrad International Hospital, Bangkok, Thailand) ,  Sukasem Chonlaphat (8MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom)
Material： Frontiers in Pharmacology (Web)
Volume： 13  Page： 835136  Publication year： 2022 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Many drugs are being administe...

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Thesaurus term： gene ,  drug ,  drug interaction ,  pharmacokinetics ,  clinical trial ,  pharmacology ,  *therapy ,  herb ,  pharmacodynamics ,  *Individualized Medicine ,  lactone ,  diene ,  alicyclic alcohol ,  bicyclic diterpene ,  polyol ,  polynuclear aromatic compound ,  hydroxy ketone ,  enzyme inhibitor
Semi thesaurus term： in silico ,  天然化合物 , 【Automatic Indexing@JST】

Author keywords (8)： COVID-19 ,  pathogenesis and severity ,  repurposed drugs ,  pharmacogenetics ,  molecular docking ,  drug-drug interactions ,  drug-herb interactions ,  precision medicine

JST classification (4)： Clinical biopharmacy  (GY01022L) ,  Clinical application of drugs acting on blood and body fluid  (GW14020X) ,  Pharmacology in general  (GW01000B) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (3)： Andrographolide ,  Warfarin ,  Efavirenz

Reference (343)：

• AckermannM., VerledenS. E., KuehnelM., HaverichA., WelteT., LaengerF. (2020). Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N. Engl. J. Med. 383, 120-128. doi: doi: 10.1056/NEJMoa2015432
• AckermannM., WerleinC., LängerF., KühnelM. P., JonigkD. D. (2021). COVID-19: Effects on the Lungs and Heart. Pathologe 42, 164-171. doi: 10.1007/s00292-021-00918-9
• AdedejiA. O., SeversonW., JonssonC., SinghK., WeissS. R., SarafianosS. G. (2013). Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry that Act by Three Distinct Mechanisms. J. Virol. 87, 8017-8028. doi: 10.1128/JVI.00998-13
• AgarwalA., RochwergB., LamontagneF., SiemieniukR. A., AgoritsasT., AskieL., et al (2020). A Living WHO Guideline on Drugs for Covid-19. BMJ 370, m3379. doi: 10.1136/bmj.m3379
• AhmadB., BatoolM., AinQ. U., KimM. S., ChoiS. (2021). Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations. Int. J. Mol. Sci. 22. doi: 10.3390/ijms22179124

Terms in the title (3)： 治療 ,  薬理遺伝学 ,  精密医療