Art

J-GLOBAL ID：202202243147104751   Reference number：22A2880047

The E3 Ubiquitin Ligase SYVN1 Plays an Antiapoptotic Role in Polycystic Ovary Syndrome by Regulating Mitochondrial Fission

E3ユビキチンリガーゼSYVN1はミトコンドリア分裂を調節することにより多嚢胞性卵巣症候群において抗アポトーシス性役割を果たす【JST・京大機械翻訳】

Author (11)： Sun Lihua (Department of Reproductive Medicine Center, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China) ,  Ye Hongjuan (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Tian Hui (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Xu Lirong (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Cai Junjie (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Zhang Caixia (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Wang Rongxiang (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Yang Hui (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Zhao Shuang (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Zhang Jiaozhi (Department of Reproductive Medicine Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China) ,  Gao Shaorong (Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, China)
Material： Oxidative Medicine and Cellular Longevity (Web)  (Oxidative Med Cell Longev (Web))
Volume： 2022  Page： Null  Publication year： 2022 
JST Material Number： U7012A  ISSN： 1942-0900  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Polycystic ovary syndrome (PCO...

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Thesaurus term： hormone ,  rat ,  metabolic error ,  internal secretion ,  GTPase ,  gene expression ,  pathological state ,  down-regulation ,  GTP binding protein ,  microtubule-associated protein ,  in vivo experiment ,  *apoptosis ,  proteasome ,  pathogenesis ,  Western blotting
Semi thesaurus term： *抗アポトーシス作用 ,  Drp1 ,  *ミトコンドリア分裂 ,  過剰発現 , 【Automatic Indexing@JST】

JST classification (2)： Biological function  (EB03040U) ,  Basic research of other drugs acting on central nervous system  (GW03120U)

Reference (40)：

• E. K. Barthelmess, R. K. Naz, "Polycystic ovary syndrome: current status and future perspective," Frontiers in Bioscience (Elite Edition), vol. 6, no. 1, pp. 104-119, 2014.
• S. Zadeh Modarres, Z. Heidar, F. Foroozanfard, Z. Rahmati, E. Aghadavod, Z. Asemi, "The effects of selenium supplementation on gene expression related to insulin and lipid in infertile polycystic ovary syndrome women candidate for in vitro fertilization: a randomized, double-blind, placebo-controlled trial," Biological Trace Element Research, vol. 183, no. 2, pp. 218-225, 2018.
• J. Zhang, Y. Bao, X. Zhou, L. Zheng, "Polycystic ovary syndrome and mitochondrial dysfunction," Reproductive Biology and Endocrinology, vol. 17, no. 1, pp. 67, 2019.
• B. Westermann, "Mitochondrial fusion and fission in cell life and death," Nature Reviews Molecular Cell Biology, vol. 11, no. 12, pp. 872-884, 2010.
• L. Tilokani, S. Nagashima, V. Paupe, J. Prudent, "Mitochondrial dynamics: overview of molecular mechanisms," Essays in Biochemistry, vol. 62, no. 3, pp. 341-360, 2018.

Terms in the title (6)： E3ユビキチンリガーゼ ,  ミトコンドリア分裂 ,  調節 ,  多嚢胞性卵巣症候群 ,  抗アポトーシス ,  性役割