Art

J-GLOBAL ID：202202253940449475   Reference number：22A1024289

T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C

免疫優性Listeriaエピトープに対するT細胞応答は,結腸直腸癌抗原,グアニリルシクラーゼCに対するワクチン指向反応を制限する【JST・京大機械翻訳】

Author (10)： Flickinger John C. Jr (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Singh Jagmohan (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Yarman Yanki (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Carlson Robert D. (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Barton Joshua R. (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Waldman Scott A. (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Waldman Scott A. (Sidney Kimmel Cancer Center, Philadelphia, PA, United States) ,  Snook Adam E. (Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States) ,  Snook Adam E. (Sidney Kimmel Cancer Center, Philadelphia, PA, United States) ,  Snook Adam E. (Department of Microbiology & Immunology, Thomas Jefferson University, Philadelphia, PA, United States)
Material： Frontiers in Immunology (Web)
Volume： 13  Page： 855759  Publication year： 2022 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The Gram-positive bacterium Li...

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Thesaurus term： optimization ,  peptide ,  Adenoviridae ,  *antigen ,  *vaccine ,  clinical trial ,  tumor antigen ,  complex (substance) ,  immunogenicity ,  tumor vaccine ,  Vaccination ,  *epitope ,  CD8 positive T cell ,  immune response ,  *Listeria ,  modification ,  *microorganism ,  animal virus ,  *Bacteria
Semi thesaurus term： immunological reaction ,  *Listeria , 【Automatic Indexing@JST】

Author keywords (5)： listeria ,  vaccine ,  immunodominance ,  colorectal cancer ,  GUCY2C

JST classification (2)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Tumor immunity  (ED03040A)

Reference (67)：

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Terms in the title (9)： 免疫優性 ,  Listeria ,  エピトープ ,  T細胞応答 ,  結腸直腸 ,  癌抗原 ,  グアニリルシクラーゼ ,  ワクチン ,  制限