Art

J-GLOBAL ID：202202276490328273   Reference number：22A1167776

Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer

がんの基礎研究,診断,治療におけるCRISPR/Cas9ベース遺伝子編集技術の応用【JST・京大機械翻訳】

Author (19)： Huimin Zhang, (Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, Department of Otolaryngology Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, China) ,  Chunhong Qin, (Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, Department of Otolaryngology Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, China) ,  Chunhong Qin, (Department of Biochemistry & Molecular Biology, Shanxi Medical University, Taiyuan, China) ,  Changming An, (Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Xiwang Zheng, (Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, Department of Otolaryngology Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, China) ,  Xiwang Zheng, (General Hospital, Clinical Medical Academy, Shenzhen University, Shenzhen, China) ,  Shuxin Wen, (Department of Otolaryngology Head & Neck Surgery, Shanxi Bethune Hospital, Taiyuan, China) ,  Wenjie Chen, (Department of Otolaryngology Head & Neck Surgery, Shanxi Bethune Hospital, Taiyuan, China) ,  Xianfang Liu, (Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Zhenghua Lv, (Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Pingchang Yang, (Research Center of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China) ,  Pingchang Yang, (Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Shenzhen, China) ,  Wei Xu, (Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China) ,  Wei Gao, (Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, Department of Otolaryngology Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, China) ,  Wei Gao, (General Hospital, Clinical Medical Academy, Shenzhen University, Shenzhen, China) ,  Wei Gao, (Department of Cell biology and Genetics, Basic Medical School of Shanxi Medical University, Taiyuan, China) ,  Yongyan Wu, (Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, Department of Otolaryngology Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, China) ,  Yongyan Wu, (Department of Biochemistry & Molecular Biology, Shanxi Medical University, Taiyuan, China) ,  Yongyan Wu, (General Hospital, Clinical Medical Academy, Shenzhen University, Shenzhen, China)
Material： Molecular Cancer (Web)
Volume： 20  Issue： 1  Page： 1-22  Publication year： 2021 
JST Material Number： U7336A  ISSN： 1476-4598  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The 2020 Nobel Prize in Chemis...

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Thesaurus term： RNA ,  tumor cell ,  protein ,  *nuclease ,  clustering ,  endonuclease ,  genome ,  gene locus ,  *gene manipulation ,  hot spot ,  palindrome ,  targeting ,  tumorigenesis
Semi thesaurus term： *CRISPR配列 ,  *遺伝子編集 ,  *CRISPR-Cas9 , 【Automatic Indexing@JST】

Author keywords (6)： Cancer research ,  CRISPR/Cas9 ,  Gene editing technology ,  Cancer stem cell ,  Cancer therapy ,  Diagnosis of cancer

JST classification (1)： Gene manipulation  (EC02050B)

Reference (200)：

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• Cell.; Lessons from the cancer genome; LA Garraway, ES Lander; 153; 2013; 17-37; 10.1016/j.cell.2013.03.002; citation_id=CR3
• Nat Rev Cancer; Applications of the CRISPR-Cas9 system in cancer biology; FJ Sánchez-Rivera, T Jacks; 15; 2015; 387-395; 10.1038/nrc3950; citation_id=CR4
• Annu Rev Pathol; Driver and passenger mutations in cancer; JR Pon, MA Marra; 10; 2015; 25-50; 10.1146/annurev-pathol-012414-040312; citation_id=CR5

Terms in the title (9)： がん ,  基礎 ,  研究 ,  診断 ,  治療 ,  CRISPR ,  Cas9 ,  遺伝子編集 ,  応用