Proj
J-GLOBAL ID:202204014052030296  Research Project code:14542684

高効率リンケージフリー分子進化創薬を目指した超高速IVC液滴作成法の開発

高効率リンケージフリー分子進化創薬を目指した超高速IVC液滴作成法の開発
Study period:2014 - 2015
Organization (1):
Research responsibility: ( , グリーンデバイス研究センター, 特任准教授 )
Research overview:
A facile bulk method is developed to generate monodisperse sub-femtoliter water-in-oil droplets (volumes ranging from 0.2 to 6.4 fL) at mega-scale and ultra-high speed (0.5×106 droplets per second) using immersed super-fine electrostatic inkjet technology. These droplets were used as sub-femtoliter in vitro compartmentalization (IVC) for biomolecule encapsulation and successive in vitro gene expression for ‘digitizing’ and linkage-free directed molecular evolution methodologies.
Terms in the title (6):
Terms in the title
Keywords automatically extracted from the title.
Research program:
Organization with control over the research:
Japan Science and Technology Agency

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