Rchr
J-GLOBAL ID：202301000300887099
Update date: Nov. 18, 2024
Kikuchi Hiroaki
キクチ ヒロアキ | Kikuchi Hiroaki
Affiliation and department：
Job title：
Assistant Professor
Research theme for competitive and other funds (5)：
- 2024 - 2027 SPPARMαを用いた、多発性嚢胞腎における嚢胞増大抑制効果の検討
- 2024 - 2027 ysregulation of AMPK signal, as the target for the renal epithelial damage in chronic kidney disease
- 2024 - 2027 Elucidation of Pathophysiology and Drug Development for Chronic Kidney Disease by Using Kidney-on-a-chip Derived from Patients
- 2024 - 2026 Non-canonical beta-catenin phosphorylation and regulation of gene expression in polycystic kidney disease
- 2023 - 2025 Non-canonical beta-catenin phosphorylation and regulation of gene expression in chronic kidney disease
Papers (45)：
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Takuya Fujimaru, Takayasu Mori, Akinari Sekine, Motoko Chiga, Shintaro Mandai, Hiroaki Kikuchi, Yutaro Mori, Yu Hara, Tamami Fujiki, Fumiaki Ando, et al. Importance of IFT140 in Patients with Polycystic Kidney Disease Without a Family History. Kidney international reports. 2024. 9. 9. 2685-2694
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Makiko Mori, Yutaro Mori, Nakao Yuki, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Yuma Waseda, et al. Adult renal tubular organoids can be produced from different human individuals in a completely same protocol. 2024
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Mari Sugimoto, Hiroaki Kikuchi, Eisei Sohara, Kavee Limbutara, Akihiro Hirakawa, Takayasu Mori, Koichiro Susa, Shuichiro Oya, Takefumi Suzuki, Soichiro Iimori, et al. Biguanides Associate with Decreased Early Mortality and Risk of Acute Kidney Injury In Hospitalized COVID-19 Patients: a nationwide retrospective cohort study in Japan. 2024
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Takayasu Mori, Takuya Fujimaru, Chunyu Liu, Karynne Patterson, Kohei Yamamoto, Takefumi Suzuki, Motoko Chiga, Akinari Sekine, Yoshifumi Ubara, Danny E Miller, et al. CFAP47 is a novel causative gene implicated in X-linked polycystic kidney disease. medRxiv : the preprint server for health sciences. 2024
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Takuya Fujimaru, Takayasu Mori, Motoko Chiga, Shintaro Mandai, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Koichiro Susa, Yuta Nakano, Takao Shoji, et al. Genetic Diagnosis of Adult Hemodialysis Patients With Unknown Etiology. Kidney international reports. 2024. 9. 4. 994-1004
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MISC (21)：
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柳川 英輝, 安藤 史顕, 原 悠, 及川 大輔, 七松 東, 鈴木 聡一郎, 藤木 珠美, 菊池 寛昭, 萬代 新太郎, 森 雄太郎, et al. LRBAは水と塩の恒常性を同時に制御する. 日本腎臓学会誌. 2024. 66. 4. 572-572
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鈴木 健文, 須佐 紘一郎, 柳 智貴, 中野 雄太, 原 悠, 藤木 珠美, 菊池 寛昭, 安藤 史顕, 萬代 新太郎, 森 雄太郎, et al. ヒトiPS細胞を用いたネフロン癆病態モデル腎オルガノイドの作製. 日本腎臓学会誌. 2024. 66. 4. 572-572
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菊池 寛昭, 蘇原 映誠, 磯部 清志, 森 崇寧, 安藤 史顕, 須佐 紘一郎, 内田 信一. βカテニンSer552残基のリン酸化がTCF/LEF転写活性の抑制を介してバゾプレシンシグナルを制御する. 日本腎臓学会誌. 2024. 66. 4. 574-574
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菊池 寛昭, 蘇原 映誠, 須佐 紘一郎, 柳 智貴, 鈴木 健文, 山本 浩平, 森 雄太郎, 安藤 史顕, 萬代 新太郎, 森 崇寧, et al. ヒト近位尿細管におけるULK1-AMPKシグナル破綻はヒト慢性腎臓病の重症度に関連する. 日本腎臓学会誌. 2024. 66. 4. 580-580
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森 槙子, 森 雄太郎, 仲尾 祐輝, 萬代 新太郎, 原 悠, 藤木 珠美, 菊池 寛昭, 安藤 史顕, 森 崇寧, 須佐 紘一郎, et al. SGLT2阻害薬の尿細管上皮に対する腎保護作用の解明. 日本腎臓学会誌. 2024. 66. 4. 582-582
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Books (2)：
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腎と透析 診療指針 2016
東京医学社 2016
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WNK-WNKキナーゼによる輸送体制御
腎臓内科・泌尿器科 2016
Lectures and oral presentations (30)：
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ULK1によるAMPKのAMP感受性制御の発見とCKDにおける破綻の解明
(日本腎臓学会誌)
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Alox15 knock-outマウスは、腎臓におけるPGD2の増加を介してCKDの腎障害及び線維化を改善する
(日本腎臓学会誌)
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腎生検にてネフロン癆が疑われた成人症例における臨床・病理所見と遺伝的背景の関係
(日本腎臓学会誌)
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Alox15 KOマウスは、CKDの腎障害及び線維化に抵抗性を示す
(日本腎臓学会誌)
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エネルギー不全感知障害が慢性腎臓病の新たな治療標的である
(第5回腎臓セミナー・Nexus Japan プロシーディング 「YIA 受賞講演」)
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Education (4)：
- 2015 - 2019 Tokyo Medical and Dental University Graduate School, Division of Medical Sciences
- 2015 - 2019 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Nephrology
- 2004 - 2010 Tokyo Medical and Dental University Faculty of Medicine School of Medicine
- 2001 - 2004 東京学芸大学附属高校
Work history (7)：
- 2024/04 - 現在 Tokyo Medical and Dental University Tokyo Medical and Dental University Hospital Department of Hemopurification Assistant Professor
- 2023/04 - 2024/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Endowed Departments Department of Nephrology and Regional Health(ibaraki) Assistant Professor
- 2019/07 - 2023/03 National Institute of Health Epithelial Systems Biology Laboratory, National Heart, Lung and Blood Institute Research Fellow
- 2015/04 - 2019/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Systemic Organ Regulation Nephrology Graduate Student
- 2014/04 - 2015/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
- 2012/04 - 2014/03 Yokosuka Kyosai Hospital Nephrology
- 2010/04 - 2012/03 Japanese Red Cross Musashino Hospital.
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Awards (11)：
- 2024/07 - Outstanding Presentation Award at the 67th Annual Meeting of the Japanese Society of Nephrology
- 2024/05 - UJA (United Japanese researchers Around the world) 2024 UJA Outstanding Paper Award Signaling Mechanisms in Renal Compensatory Hypertrophy Revealed by Multi-Omics
- 2024/01 - Best English Presentation Award at the 33rd Vasopressin-Oxytocin Research Conference Vasopressin-mediated beta-catenin phosphorylation and regulation of gene expression in renal collecting duct
- 2023/08 - 東京医科歯科大学 医科同窓会 第37回 東京医科歯科大学 医科同窓会 研究奨励賞 マルチオミクス解析を用いた腎肥大メカニズムの解明
- 2019/08 - 日本腎臓学会 第5回腎臓セミナー・Nexus Japan 菊池寛昭. Young Investigator Awards
- 2019/08 - Japanese Society of Nephrology Young Investigator Award(YIA) Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease
- 2019/05 - 東京医科歯科大学医師会 菊池寛昭. 平成30年 東京医科歯科大学医師会賞
- 2019/05 - Tokyo Medical and Dental University Medical Association Tokyo Medical and Dental University Medical Association Award Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease
- 2019/02 - The 8th Chronic Kidney Disease Frontier (Nagoya) Hiroaki Kikuchi. CKD Frontier Award AMPK activation bypassing AMP sensing mechanism is a novel therapeutic strategy for chronic kidney disease
- 2019/02 - Japanese Society of Nephrology CKD frontier Award Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease
- 2018/02 - ISN Frontiers Meetings 2018 Hiroaki Kikuchi. ISN Frontiers Young Investigators Travel Grants Association between Body Mass Index and In-hospital Mortality in Emergently Hospitalized Dialysis-Independent CKD Patients; A Nationwide Retrospective Cohort Study in Japan
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Association Membership(s) (3)：
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