Rchr
J-GLOBAL ID：202301002720487412
Update date: May. 12, 2025
Suzuki Shodai
スズキ ショウダイ | Suzuki Shodai
Affiliation and department：
Job title：
Post-doctoral Scholar
Research field (3)：
Cell biology
, Pharmaceuticals - health and biochemistry
, Molecular biology
Research keywords (6)：
Notch signal
, CADASIL
, Protein Aggregation
, Aging
, Gylcosylation
, Cerebral Microenvironment
Research theme for competitive and other funds (5)：
- 2022 - 2025 The Analysis of the mechanisms of the aging-mediated accumulation of CADASIL-mutated NOTCH3 protein
- 2023 - 2024 CADASIL 病態機構における NOTCH3 糖鎖修飾の影響の解析
- 2022 - 2023 糖修飾依存的なCADASIL型NOTCH3変異タンパク質蓄積の分子機構の解析
- 2021 - 2022 細胞老化がCADASIL病態形成を促進するのか?
- 2020 - 2021 糖修飾が関与するCADASIL変異NOTCH3タンパク質蓄積メカニズムの解明
Papers (4)：
-
Shodai Suzuki, Motoyuki Itoh. Synergistic effects of mutation and glycosylation on disease progression. Frontiers in molecular biosciences. 2025. 12. 1550815-1550815
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Shodai Suzuki, Taiki Mashiko, Yohei Tsukamoto, Miyu Oya, Yuki Kotani, Saki Okawara, Takemi Matsumoto, Yuki Mizue, Hideyuki Takeuchi, Tetsuya Okajima, et al. The N-acetylglucosaminyltransferase Radical fringe contributes to defects in JAG1-dependent turnover and signaling of NOTCH3 CADASIL mutants. Journal of Biological Chemistry. 2024. 300. 10
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Kota Fujiki, K. Tanabe, S. Suzuki, A. Mochizuki, M. Mochizuki-Kashio, T. Sugaya, T. Mizoguchi, M. Itoh, A. Nakamura-Ishizu, H. Inamura, et al. Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggrephagy in HK-2 cells. Scientific Reports. 2024. 14. 1. 14552-14552
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Shodai Suzuki, Satoshi Hiura, Taiki Mashiko, Takemi Matsumoto, Motoyuki Itoh. Lunatic fringe promotes the aggregation of CADASIL NOTCH3 mutant proteins. Biochemical and Biophysical Research Communications. 2021. 557. 302-308
MISC (1)：
Education (3)：
- 2021 - 2024 Chiba University Graduate School of Medical and Pharmaceutical Sciences
- 2019 - 2021 Chiba University Graduate School of Medical and Pharmaceutical Sciences
- 2015 - 2019 Chiba University Faculty of Pharmaceutical Sciences
Professional career (1)：
- Ph.D. (Pharmacy) (Chiba University)
Work history (3)：
- 2025/01 - 現在 Northwestern University Feinberg School of Medicine Post-doctoral Scholar
- 2024/04 - 2025/03 Japan Society for the Promotion of Science
- 2022/04 - 2024/03 Japan Society for the Promotion of Science
Awards (3)：
- 2024/03 - 千葉大学卓越大学院プログラム 革新医療創生CHIBA卓越大学院 優秀学生賞
- 2023/04 - 千葉大学卓越大学院プログラム 革新医療創生CHIBA卓越大学院 優秀学生賞
- 2021 - フナコシ株式会社 船越龍太賞
Association Membership(s) (1)：
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