Rchr
J-GLOBAL ID：202301013695285526   Update date: Sep. 26, 2024

Fujita Toshiro

藤田 敏郎 | Fujita Toshiro
Affiliation and department：
Research Center for Advanced Science and Technology, The University of Tokyo Clinical Epigenetics

About Research Center for Advanced Science and Technology, The University of Tokyo Clinical Epigenetics


Job title： Fellow
Research field  (1)： Nephrology
Research theme for competitive and other funds  (38)：
  • 2020 - 2022 Integrative elucidation of lifestyle diseases using the epigenomic memory of kidney cells
  • 2018 - 2020 Development of a new treatment for diabetic nephropathy by siRNA delivery using nanocarriers
  • 2015 - 2020 Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction
  • 2015 - 2019 Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseases
  • 2016 - 2018 Exploration of gluco- and mineralocorticoid-dependent sodium transporter system involved in salt sensitive hypertension
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Papers (175)：
  • Takeshi Marumo, Naoto Yoshida, Noriko Inoue, Masayuki Yamanouchi, Yoshifumi Ubara, Shinji Urakami, Takeshi Fujii, Yutaka Takazawa, Kenichi Ohashi, Wakako Kawarazaki, et al. Aberrant proximal tubule DNA methylation underlies phenotypic changes related to kidney dysfunction in patients with diabetes. American journal of physiology. Renal physiology. 2024. 327. 3. F397-F411
  • Liffert Vogt, Francine Z Marques, Toshiro Fujita, Ewout J Hoorn, A H Jan Danser. Novel mechanisms of salt-sensitive hypertension. Kidney international. 2023. 104. 4. 690-697
  • Toshiro Fujita. Recent Advances in Hypertension: Epigenetic Mechanism Involved in Development of Salt-Sensitive Hypertension. Hypertension (Dallas, Tex. : 1979). 2023. 80. 4. 711-718
  • Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Wakako Kawarazaki, Shigeyoshi Oba, Takeshi Marumo, Atsu Aiba, Toshiro Fujita. Rac1 deficiency impairs postnatal development of the renal papilla. Scientific reports. 2022. 12. 1. 20310-20310
  • Daigoro Hirohama, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Wakako Kawarazaki, Wataru Fujii, Shigeyoshi Oba, Shigeru Shibata, Takeshi Marumo, Toshiro Fujita. Activation of Rac1-Mineralocorticoid Receptor Pathway Contributes to Renal Injury in Salt-Loaded db/db Mice. Hypertension (Dallas, Tex. : 1979). 2021. 78. 1. 82-93
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MISC (54)：
  • 西本 光宏, 水野 理介, 藤田 敏郎, 一色 政志. 血管内皮における細胞内カルシウムセンサーSTIM1による血圧調節機構の解析. 日本高血圧学会総会プログラム・抄録集. 2019. 42回. 222-222
  • 広浜 大五郎, 鮎澤 信宏, 上田 浩平, 西本 光宏, 河原崎 和歌子, 渡邉 篤史, 下澤 達雄, 丸茂 丈史, 柴田 茂, 藤田 敏郎. 腎pendrinの発現機構と血圧調節における役割の解明. 日本内分泌学会雑誌. 2017. 93. 4. 1377-1377
  • 西本光宏, 大津洋, 丸茂丈史, 河原崎和歌子, 鮎澤信宏, 上田浩平, 広浜大五郎, 渡邉篤史, 藤田敏郎. Eplerenoneは塩分過剰摂取によるRA系阻害抵抗性腎障害を抑制する-EVALUATE試験サブ解析-. 日本腎臓学会誌. 2015. 57. 3. 509-509
  • Masashi Isshiki, Risuke Mizuno, Mitsuhiro Nishimoto, Toshiro Fujita. A FRET-based Sensor Detects Caveolae as Spatially Distinct Ca2+Stores in Endothelial Cells. CIRCULATION. 2012. 126. 21
  • Risuke Mizuno, Masashi Isshiki, Mitsuhiro Nishimoto, Toshiro Fujita. High Salt Inhibits Lymphatic Transport Function Through Regulation Of Na plus -K plus -ATPase Activity. CIRCULATION. 2012. 126. 21
ｍore...
Education (1)：
  • 1966 - 1972 Keio University School of Medicine
Work history (10)：
  • 2018/04 - 現在 東京大学先端科学技術研究センター フェロー
  • 2012/06 - 現在 The University of Tokyo
  • 2018/04 - 2023/03 Shinshu University
  • 2012/04 - 2013/03 東京大学先端科学技術研究センター 臨床エピジェネテイクス講座 特任教授
  • 1997/04 - 2012/03 東京大学大学院医学研究科 内科学(腎臓・内分泌内科) 教授
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Awards (11)：
  • 2022 - 日本腎臓学会 上田賞
  • 2019 - American Society of Nephrology Homer W. Smith Award
  • 2015 - 日本医師会 日本医師会医学賞
  • 2015 - 紫綬褒章
  • 2014 - 国際高血圧学会 Franz Volhard Award
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