Kato Takashi

カトウタカシ | Kato Takashi

Affiliation and department：
Job title： Assistant professor

Research field (1)： Immunology

Research keywords (3)： STING (Stimulator of type I IFN genes) , Dendritic Cells , Autoinflammatory diseases

Research theme for competitive and other funds (2)：

2023 - 2025 Elucidation of molecular immunological abnormalities in the mouse model of autoinflammatory diseases
2021 - 2024 モデルマウスを用いた自己炎症性疾患の病態解明

Papers (9)：

Izumi Sasaki, Yuri Fukuda-Ohta, Chihiro Nakai, Naoko Wakaki-Nishiyama, Chizuyo Okamoto, Daisuke Okuzaki, Shuhei Morita, Shiori Kaji, Yuki Furuta, Hiroaki Hemmi, et al. A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages. Cell Reports. 2024. 43. 4. 113981-113981
Takashi Kato, Izumi Sasaki, Tsuneyasu Kaisho. Mouse model of autoinflammatory disease with dysfunction of intracellular DNA sensor system. JSIAD Journal. 2024. 3. 1. 2-7
Izumi Sasaki, Yuri Fukuda-Ohta, Chihiro Nakai, Naoko Wakaki-Nishiyama, Chizuyo Okamoto, Takashi Orimo, Daisuke Okuzaki, Shuhei Morita, Shiori Kaji, Yuki Furuta, et al. A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages. 2023
Izumi Sasaki, Takashi Kato, Hiroaki Hemmi, Yuri Fukuda-Ohta, Naoko Wakaki-Nishiyama, Asumi Yamamoto, Tsuneyasu Kaisho. Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis. Frontiers in Immunology. 2022. 13
Nobuo Kanazawa, Hiroaki Hemmi, Noriko Kinjo, Hidenori Ohnishi, Jun Hamazaki, Hiroyuki Mishima, Akira Kinoshita, Tsunehiro Mizushima, Satoru Hamada, Kazuya Hamada, et al. Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency. Nature Communications. 2021. 12. 1

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MISC (7)：

田村志宣, 田村志宣, 山下友佑, 小浴秀樹, 加藤喬, 岩淵貞弘, 佐々木泉, 橋本真一, 改正恒康. Hypomorphic mutation of Lig4 gene in mice contributes to intestinal inflammation driven by skewing Th1 cells. 日本免疫不全・自己炎症学会雑誌(Web). 2023. 2. 2
改正恒康, 金澤伸雄, 邊見弘明, 佐々木泉, 加藤喬, 山本明日美. 和歌山からの研究発信自己炎症性疾患. 和歌山医学. 2022. 73. 4. 135-135
山本明日美, 加藤喬, 佐々木泉, 改正恒康. 核酸センサーを介した自然免疫応答に関与する新規分子機構の解明. 和歌山医学. 2022. 73. 4. 151-152
加藤喬, 折茂貴是, 大田有里[福田], 西山奈央子, 中井千尋, 佐々木泉, 村上康平, 邊見弘明, 本田吉孝, 井澤和司, et al. COPA症候群の新規モデルマウスにおけるSTINGの活性化とT細胞の異常. 日本免疫不全・自己炎症学会雑誌. 2022. 1. 2. 71-71
佐々木泉, 中井千尋, 大田有里, 西山奈央子, 森田修平, 奥崎大介, 三並桃佳, 林茉里, 張江伊水, 田中日向子, et al. コレラ毒素による免疫アジュバント活性における小胞体ストレスセンサーIRE1αの機能的意義. 日本がん免疫学会総会プログラム・抄録集. 2021. 25回. 138-138

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Lectures and oral presentations (10)：

Impairment of plasma cell generation in mice carrying a proteasome subunit β1i missense
(The 3rd Japan and Australia Meeting on Cell Death 2023 2023)
Dendritic and T cell abnormalities in an autoinflammatory disease with interstitial lung disease and type I interferonopathy caused by impaired protein trafficking
(2022)
Activation of type I Interferon signaling in dendritic cells and T cells of the mouse model of COPA syndrom
(2022)
Dendritic cells and T cell abnormalities in a novel mouse model of COPA syndrome
(JSICR MMCB 2022 Joint Symposium)
COPA症候群の新規モデルマウスにおけるSTINGの活性化とT細胞の異常
(第5回日本免疫不全・自己炎症学会総会・学術集会 2022)

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Education (2)：

Professional career (1)：

Work history (4)：

2024/04 - 現在 Department of Rheumatology and Clinical Immunology, Wakayama Medical University Assistant Professor
2022/12 - 2024/03 Wakayama Medical University
2021/04 - 2022/11 日本学術振興会特別研究員DC1
2018/04 - 2020/03 和歌山県立医科大学附属病院卒後臨床研修センター初期臨床研修医

Awards (4)：

Association Membership(s) (3)：

日本免疫毒性学会 , 日本免疫不全・自己炎症学会 , 日本免疫学会

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