Rchr
J-GLOBAL ID:202301014933576557   Update date: Oct. 01, 2024

Lucena-Cacace Antonio

ルセナ カカセ アントニオ | Lucena-Cacace Antonio
Affiliation and department:
Job title: Associate Professor
Research field  (10): Hematology and oncology ,  Medical biochemistry ,  Tumor biology ,  Cardiology ,  Biomedical engineering ,  Genetics ,  Developmental biology ,  Applied molecular and cellular biology ,  Molecular biology ,  Cell biology
Research keywords  (11): Regenerative Medicine ,  Cell Cycle ,  Aging ,  Cardiovascular Biology ,  iPSCs ,  Disease Mechanisms ,  Precision medicine ,  Tissue Plasticity ,  Tissue Engineering ,  Cancer Stem Cells ,  Oncology
Research theme for competitive and other funds  (3):
  • 2024 - 2027 Improving Functional Regeneration and Engraftment of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells by Brief Cycles of Transient Reprogramming
  • 2022 - 2024 Generation of highly regenerative human induced pluripotent stem cell-derived epicardial cells for cardiac repair and regeneration
  • 2020 - 2022 Human induced pluripotent stem cell derived cardiomyocyte maturation by DNA integrative free-delivery of key regulators
Papers (23):
  • Yutaro Miyoshi, Antonio Lucena-Cacace, Yu Tian, Yasuko Matsumura, Kanae Tani, Misato Nishikawa, Megumi Narita, Takeshi Kimura, Koh Ono, Yoshinori Yoshida. SMAD3 mediates the specification of human induced pluripotent stem cell-derived epicardium into progenitors for the cardiac pericyte lineage. Stem Cell Reports. 2024
  • Antonio Lucena-Cacace, Yu Tian, Yoshinori Yoshida. Generation of 3D-Multicellular Human iPSC-Heart Organoids for the Noninvasive Assessment of Cardiac Fibrosis. Methods in Molecular Biology. 2024. 35-48
  • D. Otero-Albiol, J. M. Santos-Pereira, A. Lucena-Cacace, C. Clemente-González, S. Muñoz-Galvan, Y. Yoshida, A. Carnero. Hypoxia-induced immortalization of primary cells depends on Tfcp2L1 expression. Cell Death & Disease. 2024. 15. 2
  • Yuta Tsujisaka, Takeshi Hatani, Chikako Okubo, Ryo Ito, Azuma Kimura, Megumi Narita, Kazuhisa Chonabayashi, Shunsuke Funakoshi, Antonio Lucena-Cacace, Taro Toyoda, et al. Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting. Stem cell reports. 2022. 17. 7. 1772-1785
  • Julia Junghof, Yuta Kogure, Tian Yu, Eva María Verdugo-Sivianes, Megumi Narita, Antonio Lucena-Cacace, Yoshinori Yoshida. CDH18 is a fetal epicardial biomarker regulating differentiation towards vascular smooth muscle cells. NPJ Regenerative medicine. 2022. 7. 1. 14-14
more...
Professional career (3):
  • Ph.D. in Biomedicine (Molecular Oncology) (University of Seville)
  • M.Sc. in Biomedical Research (University of Seville)
  • B.Sc. Biochemistry (University of Seville, Medical School)
Work history (3):
  • 2024/04 - 現在 Osaka University Premium Research Institute for Human Metaverse Medicine (PRIMe) Associate Professor
  • 2022/04 - 2024/04 Kyoto University Center for iPS Cell Research and Application (CiRA) Assistant Professor
  • 2018/01 - 2022/03 Kyoto University Center for iPS Cell Research and Application (CiRA) Postdoctoral Researcher
Awards (4):
  • 2023/01 - iPS Cell Research Fund CiRA Encouragement Award 2022
  • 2022/03 - University of Seville Ph.D. extraordinary award (2016-2017)
  • 2012 - Göttinger Experimentallabor für junge Leute Research launching scholarship XLAB
  • 2011 - Spanish Association for Cancer Research National fellowship on Cancer Research (AECC)
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