Rchr
J-GLOBAL ID：202301018567040440
Update date: Dec. 06, 2024
Toyama Yuki
トヤマ ユウキ | Toyama Yuki
Affiliation and department：
Research field (4)：
Structural biochemistry
, Biophysics
, Pharmaceuticals - analytical and physicochemistry
, Molecular biochemistry
Research theme for competitive and other funds (4)：
- 2024 - 2027 DDXヘリカーゼによるRNA構造リモデリング機構の解明
- 2022 - 2022 Probing the structural dynamics of human mitochondrial protease HtrA2 by methyl-TROSY NMR
- 2021 - 2022 ミトコンドリアプロテアーゼHtrA2の活性化機構の解明
- 2019 - 2021 熱ショック因子の温度感知機構の構造生物学的解明
Papers (29)：
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Debajyoti De, Nemika Thapliyal, Ved Prakash Tiwari, Yuki Toyama, D. Flemming Hansen, Lewis E. Kay, Pramodh Vallurupalli. Mapping the FF domain folding pathway via structures of transiently populated folding intermediates. Proceedings of the National Academy of Sciences. 2024
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Yuki Toyama, Ichio Shimada. Quantitative analysis of the slow exchange process by 19F NMR in the presence of scalar and dipolar couplings: applications to the ribose 2′-19F probe in nucleic acids. Journal of Biomolecular NMR. 2024
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Yuki Toyama, Ichio Shimada. NMR characterization of RNA binding property of the DEAD-box RNA helicase DDX3X and its implications for helicase activity. Nature Communications. 2024
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Robert W. Harkness, Huaying Zhao, Yuki Toyama, Peter Schuck, Lewis Kay. Exploring Host-Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR. Journal of the American Chemical Society. 2024
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Atul Kaushik Rangadurai, Yuki Toyama, Lewis E. Kay. Sometimes pulses just have to be perfect - An example based on the measurement of amide proton transverse relaxation rates in proteins. Journal of Magnetic Resonance. 2023. 349. 107412-107412
ｍore...
MISC (5)：
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岩原 淳二, 外山侑樹. NMRを用いた生体高分子表面周辺静電ポテンシャルの直接測定. 日本核磁気共鳴学会機関誌. 2024. 13. 2. 86-92
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Yuki TOYAMA. Molecular Mechanisms of Membraneless Organelle Formation: Insights from NMR-Based Measurements of Electrostatic Potentials. Seibutsu Butsuri. 2023. 63. 5. 276-280
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外山侑樹, 嶋田一夫, 西田紀貴. RAC1発がん性変異体の動的分子機構. 細胞. 2023. 55. 3
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外山侑樹, Lewis Kay. 混合安定同位体標識を活用したタンパク質オリゴマーのアロステリック共役機構のNMR解析. 分光研究. 2023. 72. 1
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外山侑樹, 嶋田一夫. G蛋白質共役受容体 がんとG蛋白質変異:動的分子メカニズムの解明. 脳神経内科(神経内科). 2021. 94. 4. 488
Education (1)：
- 2012 - 2015 The University of Tokyo Graduate School of Pharmaceutical Sciences
Professional career (1)：
- Ph.D. (Pharmaceutical Sciences) (The University of Tokyo)
Work history (5)：
- 2024/09 - 現在 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 2022/10 - 2024/08 RIKEN RIKEN Center for Biosystems Dynamics Research Researcher
- 2019/04 - 2022/09 University of Toronto Postdoctoral Researcher,
- 2018/05 - 2019/03 The University of Tokyo Graduate School of Pharmaceutical Sciences Project Researcher
- 2015/04 - 2018/04 Japan Biological Informatics Consortium Project Researcher
Awards (2)：
- 2018/05 - JMR Award
- 2015/11 - 日本核磁気共鳴学会 若手ポスター最優秀賞 (JEOL RESONANCE賞)
Association Membership(s) (3)：
日本生物物理学会
, 日本薬学会
, 日本核磁気共鳴学会
