Art

J-GLOBAL ID：202302213663300208   Reference number：23A2878002

Clinical Performance of Oral Anticoagulants in Elderly with Atrial Fibrillation and Low Body Weight: Insight into Italian Cohort of PREFER-AF and PREFER-AF Prolongation Registries

心房細動および低体重の高齢者における経口抗凝固薬の臨床性能: PREFER-AFおよびPREFER-AF延長登録のイタリアコホートへの洞察【JST・京大機械翻訳】

Author (7)： Russo Vincenzo (Cardiology Unit, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”-Monaldi Hospital, 80131 Naples, Italy) ,  Attena Emilio (Cardiology Unit, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”-Monaldi Hospital, 80131 Naples, Italy) ,  Baroni Matteo (Cardiologia 3-A. De Gasperis Cardio Center, ASST GOM Niguarda Ca’Granda, Piazza dell’Ospedale Maggiore 3, 20162 Milan, Italy) ,  Trotta Roberta (Medical Affairs Department, Daiichi Sankyo, 00142 Rome, Italy) ,  Manu Marius Constantin (Daiichi Sankyo Europe GmbH, Zielstattstr. 48, 81379 Munich, Germany) ,  Kirchhof Paulus (Institute of Cardiovascular Sciences, University of Birmingham, Birmingham B15 2TT, UK) ,  Caterina Raffaele De (Chair of Cardiology, University of Pisa, Lungarno Antonio Pacinotti, 43, 56126 Pisa, Italy)
Material： Journal of Clinical Medicine (Web)
Volume： 11  Issue： 13  Page： 3751  Publication year： 2022 
JST Material Number： U7214A  ISSN： 2077-0383  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Background: Elderly patients a...

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Thesaurus term： safety ,  risk ,  insulin ,  hemorrhage ,  *auricular fibrillation ,  cardiac insufficiency ,  morbidity ,  patient ,  cerebral apoplexy ,  embolism ,  *population(statistics) ,  risk factor ,  cause of death ,  anticoagulation therapy
Semi thesaurus term： エンドポイント , 【Automatic Indexing@JST】

Author keywords (6)： oral anticoagulants ,  elderly ,  safety ,  body weight ,  atrial fibrillation ,  effectiveness

JST classification (2)： Drug therapy(=pharmacotherapy)for cardiovascular system diseases  (GJ05020M) ,  Clinical application of drugs acting on blood and body fluid  (GW14020X)

Reference (19)：

• Park, C.S.; Choi, E.K.; Kim, H.M.; Lee, S.R.; Cha, M.J.; Oh, S. Increased risk of major bleeding in underweight patients with atrial fibrillation who were prescribed non-vitamin K antagonist oral anticoagulants. Heart Rhythm 2017, 14, 501-507.
• Yanagisawa, S.; Inden, Y.; Yoshida, N.; Kato, H.; Miyoshi-Fujii, A.; Mizutani, Y.; Ito, T.; Kamikubo, Y.; Kanzaki, Y.; Hirai, M.; et al. Body mass index is associated with prognosis in Japanese elderly patients with atrial fibrillation: An observational study from the outpatient clinic. Heart Vessel. 2016, 31, 1553-1561.
• Boonyawat, K.; Caron, F.; Li, A.; Chai-Adisaksopha, C.; Lim, W.; Iorio, A.; Lopes, R.D.; Garcia, D.; Crowther, M.A. Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: A systematic review and meta-analysis. J. Thromb. Haemost. 2017, 15, 1322-1333.
• De Caterina, R.; Lip, G.Y.H. The non-vitamin K antagonist oral anticoagulants(NOACs) and extremes of body weight-A systematicliterature review. Clin. Res. Cardiol. 2017, 106, 565-572.
• Russo, V.; Attena, E.; Di Maio, M.; Carbone, A.; Parisi, V.; Rago, A.; Grieco, F.V.; Buonauro, A.; Golino, P.; Nigro, G. Non-vitamin K vs vitamin K oral anticoagulants in patients aged > 80 year with atrial fibrillation and low body weight. Eur. J. Clin. Investig. 2020, 50, e13335.

Terms in the title (8)： 心房細動 ,  低体重 ,  高齢者 ,  経口抗凝固薬 ,  臨床 ,  イタリア ,  コホート ,  洞察