Art

J-GLOBAL ID：202302283247261491   Reference number：23A1724319

Progress on role of ion channels of cardiac fibroblasts in fibrosis

線維症における心臓線維芽細胞のイオンチャンネルの役割に関する進展【JST・京大機械翻訳】

Author (4)： Xing Chenxv (Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China) ,  Bao Limeng (Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China) ,  Li Weidong (Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China) ,  Fan Hongkun (Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China)
Material： Frontiers in Physiology (Web)
Volume： 14  Page： 1138306  Publication year： 2023 
JST Material Number： U7093A  ISSN： 1664-042X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Cardiac fibrosis is defined as...

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Thesaurus term： voltage ,  electric potential ,  *heart ,  inflammation ,  collagen ,  receptor ,  cardiac insufficiency ,  dysfunction ,  deposition ,  sodium channel ,  *fibrous disease ,  therapeutic planning ,  potassium channel ,  extracellular matrix ,  myocyte
Semi thesaurus term： 筋線維芽細胞 , 【Automatic Indexing@JST】

Author keywords (8)： cardiac fibrosis ,  cardiac fibroblasts ,  ion channels Ca²⁺ ,  TRP channels ,  Piezo 1 ,  CRAC VGCCs ,  sodium channels ,  potassium channels

JST classification (1)： Cell physiology in general  (EF02010S)

Reference (228)：

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• AdapalaR. K., MinasyanA., KanugulaA. K., CappelliH. C., ParuchuriS., MeszarosG. J., et al (2017). Targeting TRPV4 channels protects heart from pathological remodeling following myocardial infarction. Circulation 136, A24061. doi: 10.1172/jci95945
• AdapalaR. K., ThoppilR. J., LutherD. J., ParuchuriS., MeszarosJ. G., ChilianW. M., et al (2013). TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals. J. Mol. Cell. Cardiol. 54, 45-52. doi: 10.1016/j.yjmcc.2012.10.016
• AguilarM., QiX. Y., HuangH., ComtoisP., NattelS. (2014). Fibroblast electrical remodeling in heart failure and potential effects on atrial fibrillation. Biophys. J. 107 (10), 2444-2455. doi: 10.1016/j.bpj.2014.10.014
• AhnM. S., EomY. W., OhJ. E., ChaS. K., ParkK. S., SonJ. W., et al (2020). Transient receptor potential channel TRPV4 mediates TGF-β1-induced differentiation of human ventricular fibroblasts. Cardiol. J. 27 (2), 162-170. doi: 10.5603/CJ.a2019.0050

Terms in the title (5)： 線維症 ,  心臓線維芽細胞 ,  イオンチャンネル ,  役割 ,  進展