Hotta Takashi

ホッタタカシ | Hotta Takashi

Affiliation and department：
Job title： Research Assistant Professor

Research field (1)： Cell biology

Research keywords (4)： Post-translational modifications (PTMs) , Tubulin code , tubulin , microtubules

Research theme for competitive and other funds (3)：

2016 - 2017 植物の枝分かれ微小管形成のin vitro再構成
2014 - 2016 How do tubulin mutations result in the organ-twisting phenotype in Arabidopsis?
2004 - 2006 高等植物細胞の微小管構築制御機構の解明

Papers (22)：

Qi Geng, Jakia Jannat Keya, Takashi Hotta, Kristen J Verhey. The kinesin-3 KIF1C undergoes liquid-liquid phase separation for accumulation of specific transcripts at the cell periphery. The EMBO journal. 2024
Qi Geng, Jakia Jannat Keya, Takashi Hotta, Kristen J Verhey. KIF1C, an RNA transporting kinesin-3, undergoes liquid-liquid phase separation through its C-terminal disordered domain. bioRxiv : the preprint server for biology. 2023
Yang Yue, Takashi Hotta, Takumi Higaki, Kristen J Verhey, Ryoma Ohi. Microtubule detyrosination by VASH1/SVBP is regulated by the conformational state of tubulin in the lattice. Current biology : CB. 2023. 33. 19. 4111-4123
Takashi Hotta, Alexandra Plemmons, Margo Gebbie, Trevor A Ziehm, Teresa Lynne Blasius, Craig Johnson, Kristen J Verhey, Jillian N Pearring, Ryoma Ohi. Mechanistic Analysis of CCP1 in Generating ΔC2 α-Tubulin in Mammalian Cells and Photoreceptor Neurons. Biomolecules. 2023. 13. 2
Takashi Hotta, Thomas S McAlear, Yang Yue, Takumi Higaki, Sarah E Haynes, Alexey I Nesvizhskii, David Sept, Kristen J Verhey, Susanne Bechstedt, Ryoma Ohi. EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules. Current biology : CB. 2022. 32. 18. 3898-3910

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Professional career (1)：

Work history (9)：

2023/09 - 現在 University of Michigan, Michigan Medicine Department of Cell and Developmental Biology Research Assistant Professor
2019/01 - 2023/08 University of Michigan, Michigan Medicine Department of Cell and Developmental Biology Research Investigator
2017/11 - 2018/12 University of Michigan, Michigan Medicine Department of Cell and Developmental Biology Research Fellow
2017/01 - 2017/11 Carnegie Institution for Science Embryology Research Fellow
2016/12 - 2016/12 Nara Institute of Science and Technology Graduate School of Biological Sciences

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