Rchr
J-GLOBAL ID：202401005680468963
Update date: Nov. 29, 2024
Yanagisawa Tatsuo
ヤナギサワ タツオ | Yanagisawa Tatsuo
Affiliation and department：
Job title：
Research Scientist
Research theme for competitive and other funds (6)：
- 2016 - 2020 Structural biochemistry of translation-related proteins from pathogenic bacteria
- 2015 - 2018 Identification of meningococcal virulence factors and the expression profile by using clinical isolates
- 2012 - 2016 Chemical biology using the protein-introduced unnatural lysine derivatives as probes
- 2012 - 2015 Systematic analyses of signal transduction systems on GltT-GltM glutamate transporter mediated invasion into the host cell in Neisseria meningitidis
- 2012 - 2015 Incorpoation of biocitin into a protein by expanding the genetic code
- 2009 - 2011 Site-specific incorporation of non-natural amino acids into proteins by using pyrrolysyl-tRNA synthetase
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Papers (34)：
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Satoshi Hasegawa, Rerina Inose, Mizuki Igarashi, Megumi Tsurumaki, Motofumi Saito, Tatsuo Yanagisawa, Akio Kanai, Teppei Morita. An internal loop region is responsible for inherent target specificity of bacterial Cold-shock proteins. RNA (New York, N.Y.). 2024
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Tatsuo Yanagisawa, Yuko Murayama, Haruhiko Ehara, Mie Goto, Mari Aoki, Shun-Ichi Sekine. Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nature communications. 2024. 15. 1. 7854-7854
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Tatsuo Yanagisawa, Eiko Seki, Hiroaki Tanabe, Yoshifumi Fujii, Kensaku Sakamoto, Shigeyuki Yokoyama. Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids. International journal of molecular sciences. 2023. 24. 7
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Eiko Seki, Tatsuo Yanagisawa, Mitsuo Kuratani, Kensaku Sakamoto, Shigeyuki Yokoyama. Fully Productive Cell-Free Genetic Code Expansion by Structure-Based Engineering of Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase. ACS synthetic biology. 2020. 9. 4. 718-732
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Hideyuki Takahashi, Naoshi Dohmae, Kwang Sik Kim, Ken Shimuta, Makoto Ohnishi, Shigeyuki Yokoyama, Tatsuo Yanagisawa. Genetic incorporation of non-canonical amino acid photocrosslinkers in Neisseria meningitidis: New method provides insights into the physiological function of the function-unknown NMB1345 protein. PloS one. 2020. 15. 8. e0237883
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MISC (48)：
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高橋 英之, 大西 真, 志牟田 健, 横山 茂之, 柳沢 達男. 選抜ワークショップ4:病原性(細胞内侵入/増殖/寄生・免疫回避)、生体防御 非天然アミノ酸クロスリンカーの髄膜炎菌への導入法を用いた機能未知の病原性因子の機能解明(Selected from Oral Session 4: Pathogenicity(Cell invasion, Proliferation, Paracitism and Immune Evasion) and Biophylaxis Examination of a meningococcal function-unknown protein with unnatural amino acid photocrosslinkers). 日本細菌学雑誌. 2022. 77. 1. 54-54
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高橋 英之, 大西 真, 横山 茂之, 柳沢 達男. 非天然アミノ酸を用いたNeisseria meningitidisの遺伝コードの拡張(Expanding the genetic code of Neisseria meningitidis with unnatural amino acids). 日本細菌学雑誌. 2020. 75. 1. 83-83
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高橋 英之, 横山 茂之, 柳沢 達男. 感染のための栄養毒性因子としての髄膜炎菌のシステイン輸送系の分析(Analyses of meningococcal cysteine transport system as a nutrient virulence factor for the infection). 日本細菌学雑誌. 2019. 74. 1. 56-56
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柳沢達男, 柳沢達男. 翻訳因子EF-Pのアミノアシル化とラムノシル化. 生化学. 2019. 91. 1
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仙石徹, 鈴木健裕, 堂前直, 渡邊千鶴, 本間光貴, 疋田泰士, 山口芳樹, 高橋英之, 横山茂之, 柳沢達男. 糖転移酵素EarP・翻訳因子EF-P複合体の構造から明らかになったEF-P(Arg32)ラムノシル化の反応メカニズム. 日本RNA学会年会要旨集. 2018. 20th
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Patents (9)：
Professional career (1)：
- Ph.D, Doctor of Science (Nagoya University)
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