Echizen Kanae

Research field (1)： Tumor biology

Research keywords (3)： Bioinfomatics , Hepatocellular carcinoma , Metabolic dysfunction-Associated Steatotic Liver Disease

Research theme for competitive and other funds (5)：

2024 - 2027 Steatohepatitic-HCCにおける脂質代謝異常と炎症誘導メカニズムの解明
2017 - 2019 Analysis of clonal expansions in gastritis tissues
2015 - 2019 Analysis on colon cancer malignant progression using novel mouse models
2015 - 2017 Functional analysis of Noxo1/Nox1 complex in gastritis and inflammation-associated gastric tumor development
2010 - 2012 グリオブラストーマ幹細胞が腫瘍形成能を維持するメカニズムの解明

Papers (11)：

Vu Thuong Huyen, Kanae Echizen, Ryota Yamagishi, Miho Kumagai, Yoshiki Nonaka, Takahiro Kodama, Tatsuya Ando, Megumu Yano, Naoki Takada, Masaki Takasugi, et al. Regular exercise suppresses steatosis-associated liver cancer development by degrading E2F1 and c-Myc via circadian gene upregulation. Genes to cells : devoted to molecular & cellular mechanisms. 2024. 29. 11. 1012-1025
Yusuke Kimura, Yukinori Koyama, Kojiro Taura, Aoi Kudoh, Kanae Echizen, Daichi Nakamura, Xuefeng Li, Nguyen Hai Nam, Yusuke Uemoto, Takahiro Nishio, et al. Characterization and role of collagen gene expressing hepatic cells following partial hepatectomy in mice. Hepatology (Baltimore, Md.). 2023. 77. 2. 443-455
Kanae Echizen, Keigo Horiuchi, Yayoi Aoki, Yoichi Yamada, Toshinari Minamoto, Hiroko Oshima, Masanobu Oshima. NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells. Oncogene. 2019. 38. 22. 4250-4263
Tae-Su Han, Dominic Chih-Cheng Voon, Hiroko Oshima, Mizuho Nakayama, Kanae Echizen, Eri Sakai, Zachary Wei Ern Yong, Kazuhiro Murakami, Liang Yu, Toshinari Minamoto, et al. Interleukin 1 Up-regulates MicroRNA 135b to Promote Inflammation-Associated Gastric Carcinogenesis in Mice. Gastroenterology. 2019. 156. 4. 1140-1155
Kosuke Funato, Tomoatsu Hayashi, Kanae Echizen, Lumi Negishi, Naomi Shimizu, Ryo Koyama-Nasu, Yukiko Nasu-Nishimura, Yasuyuki Morishita, Viviane Tabar, Tomoki Todo, et al. SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity. EMBO reports. 2018. 19. 11

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MISC (8)：

渡辺亮, 越前佳奈恵, 奥村龍哉, 松島早希. 【1細胞解析-技術と応用】応用発生・再生研究における1細胞遺伝子発現解析の現状. 医学のあゆみ. 2021. 276. 10. 1003-1009
大島浩子, 越前佳奈恵, 大島正伸. がんと自然炎症. 炎症と免疫. 2019. 27. 5. 428-432
越前佳奈恵, 坂井絵梨, 中山瑞穂, 大島浩子, 大島正伸. 【がん微小環境】がん微小環境による発がん促進機構. 細胞. 2018. 50. 5. 234-237
大島浩子, 越前佳奈恵, 中山瑞穂, 大島正伸. 【胃癌-診断・治療の最新知見-】自然免疫・慢性炎症と胃癌. 日本臨床. 2018. 76. 3. 520-525
大島浩子, 越前佳奈恵, 中山瑞穂, 大島正伸. 腫瘍とリンパ炎症性微小環境が促進する消化器がんの発生と悪性化進展. リンパ学. 2017. 40. 1. 43-47

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