Rchr
J-GLOBAL ID：202401007364168691   Update date: Oct. 11, 2024

Tsuji Naoko

ツジ ナオコ | Tsuji Naoko
Affiliation and department：
Hamamatsu University School of Medicine Blood Purification Unit, First Department of Medicine

About Hamamatsu University School of Medicine Blood Purification Unit, First Department of Medicine


Job title： Clinical Assistant Professor
Research field  (1)： Nephrology
Research keywords  (3)： Sepsis ,  Chronic Kidney Disease ,  Acute Kidney Injury
Research theme for competitive and other funds  (3)：
  • 2021 - 2022 Development of mitochondrial ROS and cell-free mitochondrial DNA as drug (BAM15)- companion biomarker pairs for sepsis induced acute kidney injury.
  • 2017 - 2018 敗血症患者のミトコンドリアDNAの検討:好中球細胞外トラップとエクソソームの解析
  • 2015 - 2018 Investigation of the role of TLR9 - IL - 17 pathway in Septic AKI
Papers (23)：
  • Naoko Tsuji, Takayuki Tsuji, Tetsushi Yamashita, Naoki Hayase, Xuzhen Hu, Peter S.T. Yuen, Robert A. Star. BAM15 treats mouse sepsis and kidney injury, linking mortality, mitochondrial DNA, tubule damage, and neutrophils. Journal of Clinical Investigation. 2023
  • Tetsushi Yamashita, Jonathan M. Street, Brianna C. Halasa, Yoshitaka Naito, Takayuki Tsuji, Naoko Tsuji, Naoki Hayase, Peter S. T. Yuen, Robert A. Star. The effect of continuous intravenous norepinephrine infusion on systemic hemodynamics in a telemetrically-monitored mouse model of sepsis. PLOS ONE. 2022
  • Naoko Tsuji, Sean Agbor-Enoh. Cell-free DNA beyond a biomarker for rejection: Biological trigger of tissue injury and potential therapeutics. The Journal of Heart and Lung Transplantation. 2021. 40. 6. 405-413
  • Temesgen E. Andargie, Naoko Tsuji, Fayaz Seifuddin, Moon Kyoo Jang, Peter S.T. Yuen, Hyesik Kong, Ilker Tunc, Komudi Singh, Ananth Charya, Kenneth Wilkins, et al. Cell-free DNA maps COVID-19 tissue injury and risk of death and can cause tissue injury. JCI Insight. 2021. 6. 7
  • Yoshitaka Naito, Takayuki Tsuji, Soichiro Nagata, Naoko Tsuji, Tomoyuki Fujikura, Naro Ohashi, Akihiko Kato, Hiroaki Miyajima, Hideo Yasuda. IL-17A activated by Toll-like receptor 9 contributes to the development of septic acute kidney injury. American journal of physiology. Renal physiology. 2019
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MISC (56)：
  • 磯部 伸介, 片橋 尚子, 石垣 さやか, 辻 尚子, 岩倉 考政, 藤倉 知行, 大橋 温, 加藤 明彦, 安田 日出夫. 腎移植後の体重,体組成の変化. 日本腎臓学会誌. 2024. 66. 4. 619-619
  • 岩倉 考政, 辻 尚子, 石垣 さやか, 磯部 伸介, 藤倉 知行, 大橋 温, 加藤 明彦, 安田 日出夫. DPP4阻害薬による腎内IGF1シグナル経路の活性化はMg欠乏下では消失する. 日本腎臓学会誌. 2024. 66. 4. 632-632
  • 江間 智映実, 岩倉 考政, 磯部 伸介, 藤倉 知行, 安田 日出夫, 石垣 さやか, 辻 尚子, 加藤 明彦, 大橋 温. DPP4阻害薬は抗Ferroptosis作用により葉酸誘発尿細管細胞死を抑制する. 日本腎臓学会誌. 2024. 66. 4. 633-633
  • 片橋 尚子, 辻 尚子, 石垣 さやか, 岩倉 考政, 磯部 伸介, 藤倉 知行, 大橋 温, 安田 日出夫. 一般住民における塩分摂取量と塩味味覚閾値の関連. 日本腎臓学会誌. 2024. 66. 4. 678-678
  • 辻 尚子, 安田 日出夫. 【AKIの病態の理解と集中治療】敗血症性AKIの発症メカニズムと治療アプローチ. ICUとCCU. 2024. 48. 4. 171-175
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Books (7)：
  • Japanese Journal of Intensive Care Medicine
    2024 ISBN:9784865175813
  • いまさら訊けない!透析患者検査値のみかた,考えかた
    中外医学社 2018 ISBN:9784498224117
  • 透析患者診療に役立つ診断と重症度判定のためのアプローチ
    日本メディカルセンター 2016 ISBN:9784888752893
  • Medical Practice 2015年臨時増刊号 病態生理と症例から学ぶ輸液ガイド
    文光堂 2015
  • 特集 AKI診療の進歩. 腎と透析 76:471-475, 2014
    東京医学社 2014
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Lectures and oral presentations  (20)：
  • Kidney disease in the elderly Japanese aged over 75 years old on Hamamatsu Kidney Biopsy Registry
    (JSN/ERA Symposium Collaboration with JSDT 2024)
  • マウス敗血症性急性腎障害におけるBAM15-mtDNAの治療薬-コンパニオンバイオマーカーペアとしての可能性
    (第34回日本急性血液浄化学会学術集会 2023)
  • 敗血症性急性腎障害における治療薬とコンパニオンバイオマーカーであるセルフリーミトコンドリアDNAと酸化ストレス.
    (第17回Biomedical Frontier Kumamoto (BMFK)-NIH in Japan 2023)
  • Diversification and challenging the limitations of septic AKI models
    (The 66th Annual Meeting of the Japanese Society of Nephrology 2023)
  • Evaluation of BAM15 on superoxide generation in sepsis AKI by in-vivo imaging.
    (American Society of Nephrology Kidney Week, 2022 2022)
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Education (2)：
  • 2012 - 2016 Hamamatsu University School of Medicine Medical Sciences Graduate School
  • 2001 - 2007 Hamamatsu University School of Medicine Faculty of Medicine School of Medicine
Work history (9)：
  • 2022/01 - 現在 Hamamatsu University Hospital Blood Purification Unit Clinical Assistant Professor
  • 2018/04 - 2022/12 National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Post Doctoral Fellow
  • 2016/09 - 2018/03 Hamamatsu University Hospital Blood Purification Unit Clinical Assistant Professor
  • 2016/04 - 2016/08 Hamamatsu University School of Medicine First Department of Medicine Medical Staff
  • 2012/04 - 2016/03 Hamamatsu University School of Medicine Medical Sciences Graduate School
Show all
Awards (5)：
  • 2022/07 - Hamamatsu Medical University Alumni Association Shomonkai 28th Hamamatsu Medical University Alumni Association Shomonkai Encouragement Award BAM15 treats mouse sepsis and kidney injury, linking mortality, mitochondrial DNA, tubule damage, and neutrophils.
  • 2017/06 - 遠江医学会 若手研究賞
  • 2017/06 - 第232回 東海地方会 優秀演題賞
  • 2015/02 - CKD フロンティア 優秀演題賞
  • 2012/06 - 第217回 東海地方会 優秀演題賞
Association Membership(s) (1)：
日本女性医師腎臓病医の会
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