Mizuno Tomoyuki

ミズノトモユキ | Mizuno Tomoyuki

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Kyoto University Graduate School of Medicine Visiting Professor

Research keywords (6)： Pharmacometrics , Systems Pharmacology , Pediatric Clinical Pharmacology , Precision Dosing , Drug Development , Personalized Medicine

Papers (122)：

Kei Irie, Phillip Minar, Jack Reifenberg, Brendan M. Boyle, Joshua D. Noe, Jeffrey S. Hyams, Tomoyuki Mizuno. Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease. Clinical pharmacology & therapeutics. 2026
Kei Irie, Tomoyuki Mizuno. Physiology-informed conditional variational autoencoder for generating pediatric virtual patients. 2026
Ronaldo Morales Junior, Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood. From PICU to NICU: Extrapolating meropenem exposure from pediatric to neonatal intensive care patients. The journal of clinical pharmacology. 2026
Alexandra Pyatt, Melissa McGowan, Ryota Tanaka, Bradley Miyagawa, Tomoyuki Mizuno, Adele Rike Shields, Annette Christianson, Patricia West-Thielke, John P. Leone, E. Steve Woodle, et al. Belatacept Pharmacokinetic Analysis of Belatacept Early Steroid Withdrawal Trial (BEST) to Clinical Outcomes and Compared With Reported BENEFIT and BENEFIT-EXT Pharmacokinetic Analysis. Clinical transplantation. 2025
Ryota Tanaka, Kei Irie, Tomoyuki Mizuno. Physiologically based pharmacokinetic modeling of antibiotics in children: Perspectives on model-informed precision dosing. Antibiotics. 2025

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MISC (19)：

島本裕子, 水野知行. 小児や乳幼児に特徴的な吸収や排泄が理由で薬物動態に影響する薬物-特集疑問を解決! 挑戦! 薬物動態Quiz ; 子ども編. 調剤と情報 = Rx info / じほう編 ; 日本薬剤師会監修. 2024. 30. 6. 781-783
島本裕子, 水野知行. 体重あたりの投与量が新生児・小児のほうが多い薬物-特集疑問を解決! 挑戦! 薬物動態Quiz ; 子ども編. 調剤と情報 = Rx info / じほう編 ; 日本薬剤師会監修. 2024. 30. 6. 777-780
水野知行, 水野知行. 生理学的薬物動態(PBPK)モデルの臨床活用~小児におけるModel-Informed Precision Dosingへの応用~. TDM研究. 2023. 40. 2
島本裕子, 島本裕子, 福島恵造, 水野知行, 水野知行, 市川肇, 黒嵜健一, 前田真一郎, 川端一功, 奥田真弘. 先天性心疾患小児患者におけるバンコマイシン母集団薬物動態解析-成長・発達遅延を考慮した薬物動態モデルの構築-. 日本小児臨床薬理学会雑誌. 2023. 36. 1
水野知行, 水野知行. シンシナティ小児病院におけるModel-Informed Precision Dosingの研究と臨床実装. 日本小児臨床薬理学会雑誌. 2023. 36. 1

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Professional career (1)：

PhD (Kyoto University)

Work history (9)：

2024 - 現在 Kyoto University Graduate School of Medicine Visiting Professor
2023 - 現在 Cincinnati Children's Hospital Medical Center Division of Translational and Clinical Pharmacology Associate Professor
2023 - 現在 University of Cincinnati College of Medicine Associate Professor
2023 - 現在 Cincinnati Children's Hospital Medical Center Pharmacometrics Center of Excellence Director
2018 - 2023 University of Cincinnati College of Medicine Assistant Professor

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Committee career (10)：

2024 - 現在 Clinical Pharmacology and Therapeutics (CPT) Editorial Board Member
2024 - 現在 American Society for Clinical Pharmacology and Therapeutics Precision Dosing Community Chair
2023 - 現在 Therapeutic Drug Monitoring Editorial Board Member
2023 - 現在 International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) Councilor
2022 - 現在 International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) Immunosuppressive Drug, Committee member

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Awards (16)：

2024 - American College of Clinical Pharmacology Tanabe Young Investigator Award
2023 - Japan Society for the Promotion of Science Invitational Fellow
2023 - International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) Elected Councilor
2023 - 科学技術分野文部科学大臣表彰若手科学者賞
2022 - Therapeutic Drug Monitoring Best Reviewer of the Year Award 2022

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