Ito Kenji

イトウケンジ | Ito Kenji

Affiliation and department：
Job title： Postdoctoral Fellow

Research field (4)： Experimental pathology , Molecular biology , Developmental biology , Genomics

Research keywords (1)： Heterochromatin, Pioneer transcription factor, Hepatocyte, βcell, Development/Differentiation, Regeneration

Research theme for competitive and other funds (7)：

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Papers (12)：

Takeshi Katsuda, Jonathan H Sussman, Kenji Ito, Andrew Katznelson, Salina Yuan, Naomi Takenaka, Jinyang Li, Allyson J Merrell, Hector Cure, Qinglan Li, et al. Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity. Nature communications. 2024. 15. 1. 1761-1761
Kenji Ito, Kenneth S Zaret. Maintaining Transcriptional Specificity Through Mitosis. Annual review of genomics and human genetics. 2022. 23. 53-71
Kenji Ito, Kohei Nagata, Sho Ohta, Yutaka Matsuda, Tomoyo Ukai, Ichiro Yasuda, Akira Ota, Ryota Kobayashi, Mio Kabata, Nao Sankoda, et al. The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets. Cell reports. 2022. 39. 4. 110721-110721
Kenji Ito, Takumi Takizawa. Nuclear Architecture in the Nervous System. Results and problems in cell differentiation. 2022. 70. 419-442
Azumi Noguchi, Kenji Ito, Yuichi Uosaki, Maky Ideta-Otsuka, Katsuhide Igarashi, Hideyuki Nakashima, Toshikazu Kakizaki, Ruri Kaneda, Hideki Uosaki, Yuchio Yanagawa, et al. Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons. Neuroscience research. 2021. 173. 22-33

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Books (3)：

Lectures and oral presentations (10)：

Histone demethylases KDM4A/4B/4C maintain H3K9me3 domains and cellular identity by inhibiting H3K9me3 spreading in differentiated cells
(2024 Summer Liver Academy Meeting (SLAM) 2024)
Manipulating heterochromatin to improve glucose responsiveness of sc-β cells
(Human Islet Research Network 2023 Annual Investigator Hybrid Meeting 2023)
Uncovering the molecular mechanism of loss of H3K9me3-heterochromatin for generating functional mature beta-cells from human pluripotent stem cells
(2022)
Identification of functional elements which the loss of H3K9me3-heterochromatin during liver and pancreatic beta cell development
(2021)
Mechanism of H3K9me3-heterochromatin loss on protein-coding genes during embryonic development
(2020)

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Professional career (1)：

Work history (3)：

2020/02 - 現在 University of Pennsylvania Kenneth S. Zaret lab, Institute for Regenerative Medicine, Department of Cell and Developmental Biology Perelman School of Medicine Postdoctoral fellow
2018/04 - 2020/01 The Institute of Medical Science, The University of Tokyo The Institute of Medical Science Center for Experimental Medicine and Systems Biology
2015/04 - 2018/03 Kyoto University Center of iPS cell Research and Application Postdoctoral fellow

Awards (6)：

2024/06 - American Society for Investigative Pathology, Inc. (ASIP) Summer Liver Acadamy Meeting (SLAM) 2024, Trainee scholar award
2018 - 45th, Annual IMSUT symposium, best poster award
2017 - CiRA CiRA retreat 2017 Outstanding Poster Award
2016 - CiRA CiRA retreat 2016 Outstanding Poster Award
2014 - KITAKANTO medical society best presenter award

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Association Membership(s) (6)：

The American Society for Investigative Pathology, Inc. (ASIP) , 日本生化学会 , 日本癌学会 , 日本エピジェネティクス研究会 , 日本分子生物学会 , 日本神経科学会

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