Art

J-GLOBAL ID：202402220728115160   Reference number：24A0012030

Identification of Triazolo-quinazolinone Derivatives as Novel and Potent Chitinase OfChi-h Inhibitors Based on Structure-Based Virtual Screening

構造に基づく仮想スクリーニングに基づくChi-h阻害剤の新規で強力なキチナーゼとしてのトリアゾロ-キナゾリノン誘導体の同定【JST・京大機械翻訳】

Author (16)： Dong Lili (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Shen Shengqiang (Tingo Exosomes Technology Company, Limited, People’s Republic of China) ,  Jiang Xi (State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, People’s Republic of China) ,  Jiang Xi (Guangdong Laboratory for Lingnan Modern Agriculture (Shenzhen Branch), Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Guangdong, People’s Republic of China) ,  Ding Baokang (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Yang Meiling (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Chen Wei (State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, People’s Republic of China) ,  Liu Yaxin (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Chen Ziyang (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Cao Qingnan (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Gao Yongming (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Ma Shujie (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Zhang Lihui (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Dong Jingao (College of Plant Protection/State Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Hebei, People’s Republic of China) ,  Yang Qing (State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, People’s Republic of China) ,  Yang Qing (Guangdong Laboratory for Lingnan Modern Agriculture (Shenzhen Branch), Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Guangdong, People’s Republic of China)
Material： Journal of Agricultural and Food Chemistry  (J Agric Food Chem)
Volume： 71  Issue： 45  Page： 17410-17419  Publication year： 2023 
JST Material Number： C0251A  ISSN： 0021-8561  CODEN： JAFCAU  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Insect chitinase, OfChi-h, fro...

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Thesaurus term： crystal structure ,  pesticide ,  insecticidal action ,  biological activity ,  *Chitinase ,  chemical compound ,  *screening (inspection) ,  controlling element ,  *virtual screening ,  Insecta ,  Arthropoda ,  invertebrate ,  aromatic amine ,  aromatic carboxylic acid ,  aromatic fluorine compound ,  aromatic chlorine compound ,  urea compound ,  carboxamide ,  phenol ether
Semi thesaurus term： Insecta , 【Automatic Indexing@JST】

Author keywords (5)： triazolo-quinazolinone ,  chitinase ,  OfChi-h ,  Ostrinia furnacalis ,  virtual screening

JST classification (2)： Pesticides to microorganisms  (FB06040Q) ,  Pesticides to weeds  (FB06030F)

Substance index (1)： Hexaflumuron

Terms in the title (6)： 仮想スクリーニング ,  阻害剤 ,  キチナーゼ ,  キナゾリノン ,  誘導体 ,  同定