Art

J-GLOBAL ID：202402233584038129   Reference number：24A0713150

Geometric parameters that affect the behavior of logic-gated CAR T cells

論理ゲートCAR T細胞の挙動に影響する幾何学的パラメータ【JST・京大機械翻訳】

Author (13)： Partin Alexander C. (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Bruno Richele (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Shafaattalab Sanam (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Vander Mause Erica (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Winters Aaron (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Daris Mark (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Gahrs Casey (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Jette Claudia A. (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  DiAndreth Breanna (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Sandberg Mark L. (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Hamburger Agnes E. (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Kamb Alexander (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States) ,  Riley Timothy P. (A2 Biotherapeutics, Inc., Agoura Hills, CA, United States)
Material： Frontiers in Immunology (Web)
Volume： 15  Page： 1304765  Publication year： 2024 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Clinical applications of CAR-T...

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Thesaurus term： interchangeability ,  antigen ,  tumor ,  receptor ,  blocking effect ,  *T cell ,  immunotherapy ,  targeting ,  cell transplantation
Semi thesaurus term： 活性化剤 ,  *論理ゲート ,  癌治療 ,  エフェクター細胞 ,  臨床応用 , 【Automatic Indexing@JST】

Author keywords (5)： logic-gate ,  CAR (chimeric antigen receptor) ,  synapse ,  T cell ,  immunotherapy

JST classification (1)： Immunotherapy for tumors  (GE03035B)

Reference (42)：

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• Abbott RC, Hughes-Parry HE, Jenkins MR. To go or not to go? Biological logic gating engineered T cells. J Immunother Cancer (2022) 10(4):e004185. doi: doi: 10.1136/jitc-2021-004185

Terms in the title (4)： 論理ゲート ,  T細胞 ,  挙動 ,  幾何学的パラメータ