Art

J-GLOBAL ID：202402268947121073   Reference number：24A0136704

Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges

年齢関連筋骨格障害に対するオリゴヌクレオチド治療: 成功と課題【JST・京大機械翻訳】

Author (6)： Nicholson Thomas A. (MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK) ,  Sagmeister Michael (Institute for Metabolism and Systems Research, University of Birmingham, Birmingham B15 2TT, UK) ,  Wijesinghe Susanne N. (MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK) ,  Farah Hussein (MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK) ,  Hardy Rowan S. (Institute for Metabolism and Systems Research, University of Birmingham, Birmingham B15 2TT, UK) ,  Jones Simon W. (MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK)
Material： Pharmaceutics (Web)
Volume： 15  Issue： 1  Page： 237  Publication year： 2023 
JST Material Number： U7258A  ISSN： 1999-4923  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Age-related disorders of the m...

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Thesaurus term： safety ,  skeletal muscle ,  cartilage ,  *oligonucleotide ,  drug therapy ,  clinical medicine ,  articular cartilage ,  synovial membrane ,  *therapy ,  osteoporosis ,  pathology ,  rheumatoid arthritis ,  gene targetting ,  sarcopenia
Semi thesaurus term： *筋骨格系疾患 , 【Automatic Indexing@JST】

Author keywords (9)： skeletal muscle ,  sarcopenia ,  osteoarthritis ,  osteoporosis ,  rheumatoid arthritis ,  oligonucleotides ,  cartilage ,  bone ,  synovium

JST classification (2)： Cell physiology in general  (EF02010S) ,  Musculoskeletal diseases  (GG03000T)

Reference (142)：

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• Nicholson, T.; Church, C.; Baker, D.J.; Jones, S.W. The role of adipokines in skeletal muscle inflammation and insulin sensitivity. J. Inflamm. 2018, 15, 9.
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Terms in the title (5)： 年齢 ,  筋骨格障害 ,  オリゴヌクレオチド ,  治療 ,  成功