Art

J-GLOBAL ID：202402283980317354   Reference number：24A0712840

A protein-miRNA biomic analysis approach to explore neuroprotective potential of nobiletin in human neural progenitor cells (hNPCs)

ヒト神経前駆細胞(hNPC)におけるノビレチンの神経保護能を調べるための蛋白質-miRNAバイオミクス解析アプローチ【JST・京大機械翻訳】

Author (17)： Jahan Sadaf (1Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al-Majmaah, Saudi Arabia) ,  Jahan Sadaf (2Health and Basic Sciences Research Center, Majmaah University, Majmaah, Saudi Arabia) ,  Ansari Uzair Ahmad (3Developmental Toxicology Laboratory, Systems Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, Uttar Pradesh, India) ,  Ansari Uzair Ahmad (4Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India) ,  Srivastava Ankur Kumar (3Developmental Toxicology Laboratory, Systems Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, Uttar Pradesh, India) ,  Aldosari Sahar (1Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al-Majmaah, Saudi Arabia) ,  Aldosari Sahar (2Health and Basic Sciences Research Center, Majmaah University, Majmaah, Saudi Arabia) ,  Alabdallat Nessrin Ghazi (1Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al-Majmaah, Saudi Arabia) ,  Alabdallat Nessrin Ghazi (2Health and Basic Sciences Research Center, Majmaah University, Majmaah, Saudi Arabia) ,  Siddiqui Arif Jamal (5Department of Biology, College of Science, University of Hail, Hail, Saudi Arabia) ,  Khan Andleeb (6Department of Biosciences, Faculty of Science, Integral University, Lucknow, India) ,  Albadrani Hind Muteb (7Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Eastern Province, Saudi Arabia) ,  Sarkar Sana (3Developmental Toxicology Laboratory, Systems Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, Uttar Pradesh, India) ,  Khan Bushra (3Developmental Toxicology Laboratory, Systems Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, Uttar Pradesh, India) ,  Adnan Mohd (5Department of Biology, College of Science, University of Hail, Hail, Saudi Arabia) ,  Pant Aditya Bhushan (3Developmental Toxicology Laboratory, Systems Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, Uttar Pradesh, India) ,  Pant Aditya Bhushan (4Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India)
Material： Frontiers in Pharmacology (Web)
Volume： 15  Page： 1343569  Publication year： 2024 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Chemical-induced neurotoxicity...

Thesaurus term： brain ,...
Semi thesaurus term： 神経変性疾患 ,...

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Author keywords (7)： sodium arsenate ,  nobiletin ,  human neural progenitor cells ,  miRNA ,  proteomics ,  neurodegeneration ,  neuroprotection

JST classification (3)： Gene expression  (EC02040Q) ,  Toxicity of organic compounds  (GZ02030Y) ,  Influence on animals  (EE05040R)

Substance index (1)： Nobiletin

Reference (50)：

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• BayoumiM., ArafaM. G., NasrM., SammourO. A. (2021). Nobiletin-loaded composite penetration enhancer vesicles restore the normal miRNA expression and the chief defence antioxidant levels in skin cancer. Sci. Rep. 11, 20197. doi: 10.1038/s41598-021-99756-1
• BraidyN., BehzadS., HabtemariamS., AhmedT., DagliaM., NabaviS. M., et al (2017). Neuroprotective effects of citrus fruit-derived flavonoids, nobiletin and tangeretin in alzheimer's and Parkinson's disease. CNS Neurol. Disord. Drug Targets 16, 387-397. doi: 10.2174/1871527316666170328113309
• CaoD. D., LiL., ChanW. Y. (2016). MicroRNAs: key regulators in the central nervous system and their implication in neurological diseases. Int. J. Mol. Sci. 17, 842. doi: 10.3390/ijms17060842

Terms in the title (8)： ヒト ,  神経前駆細胞 ,  ノビレチン ,  神経 ,  蛋白質 ,  miRNA ,  ミクス ,  解析