Art

J-GLOBAL ID：202402287148498721   Reference number：24A0113605

Relationship Between Direct Oral Anticoagulant Doses and Clinical Outcomes in Elderly Patients With Non-Valvular Atrial Fibrillation - ANAFIE Registry Sub-Analysis -

非弁膜症性心房細動を有する高齢患者における直接経口抗凝固薬投与量と臨床転帰との関係-ANAFIEレジストリーのサブ解析-

Author (18)： Akao Masaharu (Department of Cardiology, National Hospital Organization Kyoto Medical Center) ,  Inoue Hiroshi (Saiseikai Toyama Hospital) ,  Yamashita Takeshi (The Cardiovascular Institute) ,  Atarashi Hirotsugu (AOI Hachioji Hospital) ,  Ikeda Takanori (Department of Cardiovascular Medicine, Toho University Faculty of Medicine) ,  Koretsune Yukihiro (National Hospital Organization Osaka National Hospital) ,  Okumura Ken (Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center) ,  Suzuki Shinya (The Cardiovascular Institute) ,  Tsutsui Hiroyuki (Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University) ,  Toyoda Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center) ,  Hirayama Atsushi (Osaka Police Hospital) ,  Yasaka Masahiro (Department of Cerebrovascular Medicine and Neurology, Cerebrovascular Center, National Hospital Organization Kyushu Medical Center) ,  Yamaguchi Takenori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center) ,  Teramukai Satoshi (Department of Biostatistics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine) ,  Kimura Tetsuya (Primary Medical Science Department, Daiichi Sankyo Co., Ltd.) ,  Morishima Yoshiyuki (Primary Medical Science Department, Daiichi Sankyo Co., Ltd.) ,  Takita Atsushi (Data Intelligence Department, Daiichi Sankyo Co., Ltd.) ,  Shimizu Wataru (Department of Cardiovascular Medicine, Nippon Medical School, Tama Nagayama Hospital)
Material： Circulation Journal  (Circ J)
Volume： 87  Issue： 12  Page： 1765-1774(J-STAGE)  Publication year： 2023 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *auricular fibrillation ,...
Semi thesaurus term： 過少投与 ,...

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Author keywords (5)： Direct oral anticoagulants ,  Elderly ,  Non-valvular atrial fibrillation ,  Off-label dosing ,  Under-dose

JST classification (1)： Drug therapy(=pharmacotherapy)for cardiovascular system diseases  (GJ05020M)

Reference (21)：

• 1. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study. Stroke 1991; 22: 983-988.
• 2. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007; 146: 857-867.
• 3. van Walraven C, Hart RG, Connolly S, Austin PC, Mant J, Hobbs FD, et al. Effect of age on stroke prevention therapy in patients with atrial fibrillation. Stroke 2009; 40: 1410-1416.
• 4. Akao M, Ogawa H, Masunaga N, Minami K, Ishigami K, Ikeda S, et al. 10-year trends of antithrombotic therapy status and outcomes in Japanese atrial fibrillation patients: The Fushimi AF Registry. Circ J 2022; 86: 726-736.
• 5. Shen NN, Zhang C, Hang Y, Li Z, Kong LC, Wang N, et al. Real-world prevalence of direct oral anticoagulant off-label doses in atrial fibrillation: An epidemiological meta-analysis. Front Pharmacol 2021; 12: 581293.

Terms in the title (8)： 非弁膜症性心房細動 ,  高齢患者 ,  直接経口抗凝固薬 ,  投与量 ,  臨床転帰 ,  レジストリー ,  サブ ,  解析