FURUKAWA Keiko

Affiliation and department：
Job title： Professor

Research field (2)： Other , Other

Research theme for competitive and other funds (7)：

2021 - 2024 Dynamic function analysis of cancer-associated carbohydrate complexes on the cell surface and extracellular vesicles in the generation/secretion and their action
2019 - 2022 Dynamics of microenvironmental regulation by extracellular vesicles with carbohydrates and molecular cluster formation
2018 - 2022 癌関連スフィンゴ糖脂質と膜分子間の相互作用の時空間的動態と癌性形質増強機構の解析
2021 - 癌関連糖鎖を含む脂質ラフトと細胞外分泌小胞の組成及びその微小環境の制御機能の解析
2018 - 2021 Regulatory mechanisms for signals on cell membrane and under microenvironment by complex of glycosphingolipids and membrane molecules

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Papers (14)：

Action mechanisms of exosomes derived from GD3/GD2-positive glioma cells in the regulation of phenotypes and intracellular signaling: Roles of integrins. Int J Mol Sci. 2024. 25(23). 12752
Bidirectional signals generated by Siglec-7 and the crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance. iScience. 2024. 27(11):111139
The lipid globotriaosyl-ceramide promotes germinal center B cell responses and antiviral immunity. Science. 2024. 383(6684):eadg0564
Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells. Nagoya J Med. Sci. 2024
Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway. PLoS ONE. 2023. 18(2):e0281414

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Professional career (1)：

Committee career (3)：

Association Membership(s) (3)：

The Japanese Society of Carbohydrate Research , The Japanese Cancer Association , The Japanese Biochemical Society

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