Art

J-GLOBAL ID：201602210436735210   Reference number：16A0197425

Effects of febuxostat on serum urate level in Japanese hyperuricemia patients

日本人高尿酸血症患者の血清尿酸値に対するフェブキソスタットの効果

Author (17)： YAMAMOTO Tetsuya (Hyogo Coll. of Medicine, Hyogo, JPN) ,  HIDAKA Yuji (Taizankai Medical Assoc. Akasaka Central Clinic, Tokyo, JPN) ,  INABA Masaaki (Osaka City Univ. Graduate School of Medicine, Osaka, JPN) ,  ISHIMURA Eiji (Osaka City Univ. Graduate School of Medicine, Osaka, JPN) ,  OOYAMA Hiroshi (Ryogoku East Gate Clinic, Tokyo, JPN) ,  KAKUTA Hirokazu (Kakuda Clinic, Ishikawa, JPN) ,  MORIWAKI Yuji (Hyogo Coll. of Medicine, Hyogo, JPN) ,  HIGAMI Kenshi (Higami Hospital, Nara, JPN) ,  OHTAWARA Akira (San-in Rousai Hospital, Tottori, JPN) ,  HOSOYA Tatsuo (Jikei Univ. School of Medicine, Tokyo, JPN) ,  NISHIKAWA Hazime (Jikei Univ. School of Medicine, Tokyo, JPN) ,  TANIGUCHI Atsuo (Tokyo Women’s Medical Univ., Tokyo, JPN) ,  UEDA Takanori (Univ. Fukui Fac. of Medical Sci., Fukui, JPN) ,  YAMAUCHI Takahiro (Univ. Fukui Fac. of Medical Sci., Fukui, JPN) ,  FUJIMORI Shin (Teikyo Univ., Tokyo, JPN) ,  MINEO Ikuo (Toyonaka City Hospital, Osaka, JPN) ,  YAMANAKA Hisashi (Tokyo Women’s Medical Univ., Tokyo, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 25  Issue： 5  Page： 779-783  Publication year： Sep. 2015 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *xanthine oxidase enzyme inhibitor ,...

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JST classification (3)： Clinical application of enzyme preparations and inhibitor preparations  (GW21020H) ,  Clinical application of other drugs acting on metabolism  (GW13070T) ,  Treatment for metabolic diseases,nutritional diseases.  (GD05030F)

Substance index (2)： Uric Acid ,  Febuxostat

Reference (15)：

• Zhang W, Doherty M, Bardin T, Pascual E, Barskova V, Conaghan P, et al; IEULAR Standing Committee for International Clinical Studies Including Therapeutics. EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2006;65(10):1301-11.
• Becker MA, Schumacher HR Jr, Wortmann RL, MacDonald PA, Eustace D, Palo WA, et al. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med. 2005; 353(23):2450-61.
• Schumacher HR Jr, Becker MA, Wortmann RL, Macdonald PA, Hunt B, Streit J, et al. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. Arthritis Rheum. 2008;59(11):1540-8.
• Becker MA, Schumacher HR, Espinoza LR, Wells AF, MacDonald P, Lloyd E, et al. The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. Arthritis Res Ther. 2010;12(2):R63.
• Japanese Society of Gout and Nucleic Acid Metabolism. Japanese guideline for the management of hyperuricemia and gout: second edition. Gout Nucleic acid Res. 2010;34:109-44.

Terms in the title (5)： 日本人 ,  高尿酸血症 ,  患者 ,  血清尿酸値 ,  フェブキソスタット