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J-GLOBAL ID：201402276315579055   整理番号：14A0794981

消化管の移植片対宿主病治療におけるベクロメタゾンジプロピオン酸経口投与の使用:福岡骨髄移植(BMT)グループの使用経験

The Use of Oral Beclomethasone Dipropionate in the Treatment of Gastrointestinal Graft-versus-host Disease: The Experience of the Fukuoka Blood and Marrow Transplantation (BMT) Group

著者 (18件)： TAKASHIMA Shuichiro (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  ETO Tetsuya (Dep. of Hematology, Hamanomachi Hospital, JPN) ,  SHIRATSUCHI Motoaki (Dep. of Medicine and Bioregulatory Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  HIDAKA Michihiro (Dep. of Internal Medicine, National Hospital Organization Kumamoto Medical Center, JPN) ,  MORI Yasuo (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  KATO Koji (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  KAMEZAKI Kenjiro (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  OKU Seido (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  HENZAN Hideho (Dep. of Hematology, Hamanomachi Hospital, JPN) ,  TAKASE Ken (Dep. of Hematology, Hamanomachi Hospital, JPN) ,  MATSUSHIMA Takamitsu (Dep. of Medicine and Bioregulatory Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  TAKENAKA Katsuto (Center for Cellular and Molecular Medicine, Kyushu Univ. Hospital, JPN) ,  IWASAKI Hiromi (Center for Cellular and Molecular Medicine, Kyushu Univ. Hospital, JPN) ,  MIYAMOTO Toshihiro (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  AKASHI Koichi (Dep. of Medicine and Biosystemic Sci., Graduate School of Medical Sciences, Kyushu Univ., JPN) ,  AKASHI Koichi (Center for Cellular and Molecular Medicine, Kyushu Univ. Hospital, JPN) ,  TESHIMA Takanori (Center for Cellular and Molecular Medicine, Kyushu Univ. Hospital, JPN) ,  TESHIMA Takanori (Dep. of Hematology, Hokkaido Univ. Graduate School of Medicine, JPN)
資料名： Internal Medicine (Web)  (Internal Medicine (Web))
巻： 53  号： 12  ページ： 1315-1320 (J-STAGE)  発行年： 2014年 
JST資料番号： U0033A  ISSN： 1349-7235  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:日本人患者15名にベクロメタゾンジプロピオン酸を経口投...

シソーラス用語： *移植片対宿主病 ,...
準シソーラス用語： リスク分類 ,...

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分類 (3件)： 移植免疫  (ED03020E) ,  消化器の臨床医学一般  (GH01030P) ,  免疫療法薬・血液製剤の臨床への応用  (GW22020O)

物質索引 (6件)： シクロスポリン ,  タクロリムス ,  プレドニゾロン ,  ミコフェノラートモフェチル ,  メソトレキセート ,  ベクロメタゾンジプロピオナート

引用文献 (27件)：

• 1. Eriguchi Y, Takashima S, Oka H, et al. Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of alpha-defensins. Blood 120: 223-231, 2012.
• 2. Takashima S, Kadowaki M, Aoyama K, et al. The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells. J Exp Med 208: 285-294, 2011.
• 3. Hill GR, Ferrara JL. The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation. Blood 95: 2754-2759, 2000.
• 4. MacMillan ML, Weisdorf DJ, Wagner JE, et al. Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems. Biol Blood Marrow Transplant 8: 387-394, 2002.
• 5. Van Lint MT, Uderzo C, Locasciulli A, et al. Early treatment of acute graft-versus-host disease with high- or low-dose 6-methylprednisolone: a multicenter randomized trial from the Italian Group for Bone Marrow Transplantation. Blood 92: 2288-2293, 1998.

タイトルに関連する用語 (10件)： 消化管 ,  移植片対宿主病 ,  治療 ,  酸 ,  経口投与 ,  福岡 ,  骨髄移植 ,  BMT ,  グループ ,  経験