文献

J-GLOBAL ID：201702216080531321   整理番号：17A0506777

リン酸化eEF2はSUMO化され,心筋虚血再潅流中に心筋細胞アポトーシスを誘導する

Phosphorylated eEF2 is SUMOylated and induces cardiomyocyte apoptosis during myocardial ischemia reperfusion

著者 (20件)： Zhang Chao (Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, PR China) ,  Zhang Chao (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Liu Xiaojuan (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Liu Xiaojuan (Department of Pathogen Biology, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Zhang Chi (Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, PR China) ,  Zhang Chi (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Li Jingjing (Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, PR China) ,  Li Jingjing (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Guo Wanwan (Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, PR China) ,  Guo Wanwan (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Yan Daliang (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Yan Daliang (Department of Thoracic Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, PR China) ,  Yang Chen (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Yang Chen (Department of Thoracic Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, PR China) ,  Zhao Jianhua (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Zhao Jianhua (Department of Thoracic Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, PR China) ,  Wu Xiang (Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, PR China) ,  Wu Xiang (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Shi Jiahai (Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Medical College, Nantong University, Nantong, Jiangsu, PR China) ,  Shi Jiahai (Department of Thoracic Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, PR China)
資料名： Journal of Cardiology  (Journal of Cardiology)
巻： 69  号： 4  ページ： 689-698  発行年： 2017年04月 
JST資料番号： W2218A  ISSN： 0914-5087  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： イギリス (GBR)  言語： 英語 (EN)

抄録/ポイント： 心筋虚血再潅流(MIR)後の心筋細胞アポトーシスは,血行再建...

シソーラス用語： *ペプチド鎖延長因子 ,...
準シソーラス用語： *eEF2 ,...

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著者キーワード (5件)： Myocardial ischemia reperfusion ,  Cardiomyocyte apoptosis ,  eEF2 ,  Phosphorylation ,  SUMOylation

分類 (2件)： 循環系の基礎医学  (GJ01020K) ,  微生物起原の毒性  (GZ03030F)

引用文献 (40件)：

• Ong, S.B., Samangouei, P., Kalkhoran, S.B., Hausenloy, D.J. The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury. J Mol Cell Cardiol. 2015;78:23-34.
• Mangano, D.T., Browner, W.S., Hollenberg, M., London, M.J., Tubau, J.F., Tateo, I.M. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. N Engl J Med. 1990;323:1781-8.
• Hausenloy, D.J., Yellon, D.M. Targeting myocardial reperfusion injury - the search continues. N Engl J Med. 2015;373:1073-5.
• Arakawa, K., Himeno, H., Kirigaya, J., Otomo, F., Matsushita, K., Nakahashi, H., Shimizu, S., Nitta, M., Yano, H., Endo, M., Kimura, K., Umemura, S. Impact of n-3 polyunsaturated fatty acids in predicting ischemia/reperfusion injury and progression of myocardial damage after reperfusion in patients with ST-segment elevation acute myocardial infarction. J Cardiol. 2015;66:101-7.
• Joiner, M.L., Koval, O.M., Li, J., He, B.J., Allamargot, C., Gao, Z., Luczak, E.D., Hall, D.D., Fink, B.D., Chen, B., Yang, J., Moore, S.A., Scholz, T.D., Strack, S., Mohler, P.J. et al, CaMKII determines mitochondrial stress responses in heart. Nature. 2012;491:269-73.

タイトルに関連する用語 (7件)： リン酸化 ,  eEF2 ,  SUMO化 ,  心筋 ,  虚血再潅流 ,  細胞アポトーシス ,  誘導