文献

J-GLOBAL ID：201702286483391761   整理番号：17A0086610

癌へのsiRNAのデリバリーに対する機能的エクソソーム類似物:in vitroとin vivoでの評価

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation

著者 (16件)： Yang Zhaogang (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Xie Jing (School of Life Sciences, Jilin University, Changchun, 130012, China) ,  Zhu Jing (College of Pharmacy, The Ohio State University, Columbus, OH 43212, USA) ,  Kang Chen (College of Pharmacy, The Ohio State University, Columbus, OH 43212, USA) ,  Chiang Chiling (Division of Hematology, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43212, USA) ,  Wang Xinmei (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Wang Xiaobing (Tumor Biomarker Research Center, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China) ,  Wang Xiaobing (Peking Union Medical College, Beijing 100021, China) ,  Kuang Tairong (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Chen Feng (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Chen Zhou (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Zhang Aili (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Yu Bo (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA) ,  Lee Robert J. (College of Pharmacy, The Ohio State University, Columbus, OH 43212, USA) ,  Teng Lesheng (School of Life Sciences, Jilin University, Changchun, 130012, China) ,  Lee L. James (Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA)
資料名： Journal of Controlled Release  (Journal of Controlled Release)
巻： 243  ページ： 160-171  発行年： 2016年12月10日 
JST資料番号： C0308D  ISSN： 0168-3659  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 細胞外小胞の最小の亜群,エクソソームは,長距離の細胞間コミュ...

シソーラス用語： *遺伝子導入 ,...
準シソーラス用語： *siRNAデリバリー ,...

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著者キーワード (5件)： Exosome ,  siRNA ,  Electroporation ,  MCF-7 ,  Endocytosis

分類 (3件)： 遺伝子操作  (EC02050B) ,  生物学的機能  (EB03040U) ,  腫ようの実験的治療  (GE02040Y)

引用文献 (37件)：

• M. Arellano, S. Moreno, Regulation of CDK/cyclin complexes during the cell cycle, Int. J. Biochem. Cell Biol. 29 (1997) 559-573.
• J. Benito, C. Martin-Castellanos, S. Moreno, Regulation of the G1 phase of the cell cycle by periodic stabilization and degradation of the p25rum1 CDK inhibitor, EMBO J. 17 (1998) 482-497.
• CZ. Huang, WZ Huang, G. Zhang, D.L Tang, In vivo study on the effects of curcumin on the expression profiles of anti-tumour genes (VEGF, CyclinD1 and CDK4) in liver of rats injected with DEN, Mol. Biol. Rep. 40 (2013) 5825-5831.
• C.M. Sawai, J. Freund, P. Oh, D. Ndiaye-Lobry, J.C. Bretz, A. Strikoudis, L Genesca, T. Trimarchi, M.A. Kelliher, M. Clark, J. Soulier, S. Chen-Kiang, I. Aifantis, Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia, Cancer Cell 22 (2012) 452-465.
• Y. Dobashi, A. Goto, M. Fukayama, A. Abe, A. Ooi, Overexpression of cdk4/cyclin D1, a possible mediator of apoptosis and an indicator of prognosis in human primary lung carcinoma, Int. J. Cancer 110 (2004) 532-541.

タイトルに関連する用語 (6件)： 癌 ,  siRNA ,  デリバリー ,  エクソソーム ,  類似物 ,  評価