文献

J-GLOBAL ID：202502261868415482   整理番号：25A2483760

CAR-T療法:自己免疫疾患の治療における新時代の開拓【JST機械翻訳】

CAR-T therapy: pioneering a new era in the treatment of autoimmune diseases

著者 (8件)： Wu Yuanhao (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Han Luyao (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Wang Yu (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Gu Mengjiao (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Wang Yunuo (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Gao Jingyue (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Huang Hanjing (1Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China) ,  Li Chen (2Department of Dermatology, Tianjin Institute of Integrative Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China)
資料名： Frontiers in Immunology (Web)  (Frontiers in Immunology (Web))
巻： 16  ページ： 1625166  発行年： 2025年 
JST資料番号： U7074A  ISSN： 1664-3224  資料種別： 逐次刊行物 (A)
記事区分： 文献レビュー  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： 革新的な免疫療法アプローチであるCAR-T療法は,T細胞を遺...

シソーラス用語： 最適化 ,...
準シソーラス用語： 疾患活動性 ,...

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著者キーワード (5件)： キメラ抗原受容体T細胞療法 ,  CAR(キメラ抗原受容体) ,  SLE-全身性エリテマトーデス ,  自己免疫疾患 ,  副作用(副作用)

分類 (2件)： 腫ようの免疫療法  (GE03035B) ,  血液の腫よう  (GK04000M)

引用文献 (55件)：

• Kuwana Y, Asakura Y, Utsunomiya N, Nakanishi M, Arata Y, Itoh S, et al. Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions. Biochem Biophys Res Commun. (1987) 149:960-8. doi: , PMID: doi: 10.1016/0006-291x(87)90502-x
• June CH, Sadelain M. Chimeric antigen receptor therapy. N Engl J Med. (2018) 379:64-73. doi: , PMID: doi: 10.1056/NEJMra1706169
• Mikkilineni L, Kochenderfer JN. CAR T cell therapies for patients with multiple myeloma. Nat Rev Clin Oncol. (2021) 18:71-84. doi: , PMID: doi: 10.1038/s41571-020-0427-6
• June CH, O’Connor RS, Kawalekar OU, Ghassemi S, Milone MC. CAR T cell immunotherapy for human cancer. Science. (2018) 359:1361-5. doi: , PMID: doi: 10.1126/science.aar6711
• Zhang W, Feng J, Cinquina A, Wang Q, Xu H, Zhang Q, et al. Treatment of systemic lupus erythematosus using BCMA-CD19 compound CAR. Stem Cell Rev Rep. (2021) 17:2120-3. doi: , PMID: doi: 10.1007/s12015-021-10251-6

タイトルに関連する用語 (4件)： CAR-T療法 ,  自己免疫疾患 ,  治療 ,  開拓