Rchr
J-GLOBAL ID:200901000315656140   Update date: Feb. 01, 2024

Araki Norie

アラキ ノリエ | Araki Norie
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://srv02.medic.kumamoto-u.ac.jp/dept/tumor/index.html
Research field  (5): Genomics ,  Tumor biology ,  Pathobiochemistry ,  Functional biochemistry ,  Medical biochemistry
Research keywords  (7): PROTEINCHEMISTRY ,  BIOCHEMISTRY ,  Hepatic cancer ,  Neural tumor ,  Cancer Stem Cell ,  Proteomics ,  Tumor Genetics and BIology
Research theme for competitive and other funds  (163):
  • 2023 - 2026 Elucidation of transcription control mechanism by the intrinsically disordered proteins
  • 2022 - 2025 神経線維腫症の神経系細胞異常分化と腫瘍化の責任因子シグナルと治療標的の解明
  • 2022 - 2024 Target screening for cancer stem cells by a novel integrated N-terminomics and phospho- proteomics
  • 2021 - 2024 Identification of tumor-specific antigens to construct the novel combination immunotherapy
  • 2019 - 2022 神経線維腫症の神経系分化異常と腫瘍化に関わる細胞内外シグナル解明と治療戦略の構築
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Papers (133):
  • Chutima Talabnin, Thanawat Trasaktaweesakul, Pitchanun Jaturutthaweechot, Pundit Asavaritikrai, Dusit Kongnawakun, Atit Silsirivanit, Norie Araki, Krajang Talabnin. Altered O-linked glycosylation in benign and malignant meningiomas. PeerJ. 2024. 12. e16785-e16785
  • Daiki Kobayashi, Norie Araki. Quantitative proteomic analysis of elongation factor EF1A1- and EF1A2-deficient NF1-associated malignant tumor cells by SWATH-MS. Journal of Proteome Data and Methods,. 2023. in press
  • Takeshi Masuda, Norie Araki, Sumio Ohtsuki. Data for method development of water droplet-in-oil digestion approach. Journal of Proteome Data and Methods,. 2023. 5. 1
  • Niibori-Nambu A, Yamasaki Y, Kobayashi D, Angata K, Kuno A, Panawan O, Silsilivanit A, Narimatsu H, Araki N. Chondroitin sulfate modification of CSPG4 regulates the maintenance and differentiation of glioma initiating cells via integrin-associated signaling. J. Biol. Chem. 2023. in press
  • Panawan, Orasa, Silsirivanit, Ati, Chang, Chih-Hsiang, Putthisen, Siyaporn, Boonnate, Piyanard, Yokota, Taro, Nishisyama-Ikeda, Yuki, Detarya, Marutpong, Sawanyawisuth, Kanlayanee, Kaewkong, Worasak, et al. Establishment and characterization of a novel cancer stem-like cell of cholangiocarcinoma. Cancer Science. 2023. 114. 8. 3230-3246
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MISC (201):
  • Hideaki Naoe, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Norie Araki, Jiro Fujimoto, Motohiko Tanaka, Yutaka Sasaki. MULTI-OMICS ANALYSES IDENTIFY NUCLEOPHOSMIN AS A KEY REGULATOR OF APOPTOSIS RESISTANCE IN HUMAN HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2019. 70. 562A-562A
  • Norie Araki, Akiko Namubu Niibori, Daiki Kobayashi, Takuichiro Hide, Hideo Nakamura, Junichi Kuratsu. Integrated phospho-glyco-proteogenomics identified the potential clinical target signals against glioma stem cells. CANCER SCIENCE. 2018. 109. 656-656
  • Diwakar Guragain, Norie Araki, Atit Silsinivanit, Wunchana Seubwai, Ubon Cha'on. ANTI-MALARIAL DRUGS ARTESUNATE AND CHLOROQUINE INDUCE CELL DEATH BY DIFFERENT MECHANISMS IN BILE DUCT CANCER CELL LINES. ANTICANCER RESEARCH. 2018. 38. 3. 1830-1830
  • Norie Araki, Akiko N. Nambu, Atit Silsirivanit, Hiroki Okanishi, Daiki Kobayashi, Takuichiro Hide, Hideo Nakamura. Studies of key signals related to the maintenance and differentiation of glioma initiating cells by integrated-omics. CANCER SCIENCE. 2018. 109. 630-630
  • Waraporn Saentaweesuk, Norie Araki, Atit Silsirivanit, Kulthida Vaeteewoottacharn, Sopit Wongkham, Chaisiri Wongkham. Heterogeneity of E-cadherin and vimentin expressing cells is essential for highly metastatic cholangiocarcinoma cells. CANCER SCIENCE. 2018. 109. 1028-1028
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Patents (10):
Books (38):
  • プロテオミクス辞典
    講談社 2013
  • 神経線維腫症2型,母斑と母斑症,皮膚科臨床アセット15
    中山書店 2013
  • 融合プロテオミクスによる病態メカニズムの解析『創薬のためのタンパク質・プロテオミクス解析』
    羊土社 2010
  • 疾患プロテオミクスの最前線 : プロテオミクスで病気を治せるか
    メディカルドゥ 2005 ISBN:4944157320
  • 「in vitroラベル法」オンラインLC-MS法による発現プロファイル解析
    “決定版!プロテオーム解析マニュアル" 磯辺俊明・高橋信弘編集, 羊土社 2004
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Lectures and oral presentations  (152):
  • Construction of Japan Proteome Standard Repository/Database
    (jPOST 2016)
  • Extraction and validation of the specific signal network in cancer tissue cells by proteomics-based integrated -omics
    (2015)
  • Identification of TCTP-mTOR signaling as a novel biological target for Neurofibromatosis Type 1-associated tumors
    (2015)
  • The frontier of proteomics-based life science and its clinical application.
    (2015)
  • Proteome-Centric Approaches to Decipher Biological Functions
    (15th Annual International Proteomics Conference 2015)
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Works (31):
  • プロテオミクス解析による創薬ターゲットの探索
    2013 - 2015
  • 融合プロテオミクス統合マイニングソフトweb application
    2011 -
  • 最先端解析技術によるがんの体系的プロテオミクス研究戦略
    2005 - 2010
  • 脳神経系特異的な虚血性細胞死の分子シグナル制御機構の解明
    2006 - 2007
  • 悪性脳腫瘍関連遺伝子h-neuの機能解析とそれを応用した分子標的治療の開発
    2005 - 2007
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Education (3):
  • 1987 - 1992 熊本大学大学院研究員 (医学博士)
  • 1982 - 1984 Graduate School Kyushu University
  • 1978 - 1982 Kyushu University
Professional career (1):
  • 医学博士 (熊本大学)
Work history (13):
  • 2007 - 現在 Kumamoto University Graduate School of Medical Sciences Associate Professor
  • 2010 - Associate Professor,Faculty of Life Sciences(Basic medicine group),Kumamoto University
  • 2006 - 2007 Kumamoto University Graduate School of Medical Sciences Associate Professor
  • 2006 - 2007 Associate Professor,
  • 2003 - 2006 Kumamoto University School of Medicine Associate Professor
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Committee career (10):
  • 2020 - 現在 International Human Proteome Organization executive board member
  • 2018 - 現在 日本プロテオーム学会 理事
  • 2015 - 2016 日本ブロテーム学会/日本ヒトプロテオーム機構学術総会 学会年会長
  • 2009 - 2014 日本プロテオーム学会 理事
  • 2002 - 2014 日本ヒトプロテオーム機構 理事
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Awards (16):
  • 2018 - 熊本大学 熊本大学研究奨励賞
  • 2017/07 - Japan Proteome Organization Academic Aword Application of integrated proteomics for cancer research
  • 2017 - 熊本大学研究奨励賞
  • 2016 - 熊本大学研究奨励賞
  • 2015 - 熊本大学研究奨励賞
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Association Membership(s) (13):
国際プロテオーム学会(IPPC) ,  The protein society ,  米国生物学会(FASEB) ,  Methods in Protein Structure Analysis(MPSA) ,  日本プロテオーム学会 ,  The protein society ,  JAPAN SOCIETY OF CLINICAL PROTEOGENOMICS ,  JAPANESE SOCIETY FOR BIOMEDICAL MASS SPECTROMETRY ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  International Human Proteome Organization
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