Nagata Naoto

ナガタナオト | Nagata Naoto

Affiliation and department：
Job title： Lecturer
Homepage URL (1)： http://saiboubunshikinoh.wixsite.com/home

Research field (4)： Clinical pharmacy , Food sciences , Gastroenterology , Metabolism and endocrinology

Research keywords (3)：酸化ストレス , NAFLD , Energy metabolism

Research theme for competitive and other funds (5)：

2018 - 2021 酸化ストレス応答転写因子Nrf2によるエネルギー代謝調節機構の解明
2016 - 2019 Research and development for energy expending anti-obesity functional food
2015 - 2017 ブロッコリースプラウト抽出物による炎症制御及びエネルギー代謝調節機構の解明
2013 - 2014 タンパク質チロシンフォスファターゼShp2による炎症制御機構の解明
2008 - 2010 脂肪肝炎の新規治療法の開発-酪酸菌のプロバイオティクス効果の検討

Papers (73)：

Kotomi Miura, Jun-Ichi Morishige, Jotaro Abe, Pingping Xu, Yifan Shi, Zheng Jing, Naoto Nagata, Ryo Miyazaki, Naoki Sakane, Michihiro Mieda, et al. Imeglimin profoundly affects the circadian clock in mouse embryonic fibroblasts. Journal of pharmacological sciences. 2023. 153. 4. 215-220
Jun-ichi Morishige, Kazuaki Yoshioka, Hiroki Nakata, Kazuhiro Ishimaru, Naoto Nagata, Tamotsu Tanaka, Yoh Takuwa, Hitoshi Ando. Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes. Journal of Lipid Research. 2023. 100450-100450
Suratsawadee Promsuwan, Kazuki Sawamoto, Liang Xu, Mayumi Nagashimada, Naoto Nagata, Yumi Takiyama. A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated with AMPK activation. Diabetology International. 2023
Zheng Jing, Tomohiro Iba, Hisamichi Naito, Pingping Xu, Jun-Ichi Morishige, Naoto Nagata, Hironao Okubo, Hitoshi Ando. L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy. Frontiers in pharmacology. 2023. 14. 1182788-1182788
Naoto Nagata. The mechanism of sustained hepatic inflammation in non-alcoholic fatty liver disease. Journal of the Juzen Medical Society. 2023. 132. 1. 16-19

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MISC (49)：

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Patents (2)：

Books (4)：

Lectures and oral presentations (56)：

グルコラファニンによる肥満・脂肪肝に対する治療効果
(第37回日本糖尿病合併症学会抄録 2022)
Glucoraphanin has the therapeutic potential of resolving hepatic steatosis in a murine model of diet-induced obesity
(IDF2021 2021)
抗凝固薬エドキサバンの時間薬理学的検討
(第42回日本臨床薬理学会学術総会 2021)
Impact of a dosing-time-dependent effect of edoxaban on coagulation activity in rats
(2019)
Nrf2 activation by glucoraphanin alleviates high-fat diet-induced obesity and insulin resistance through adipose tissue browning.
(Environmental Response V 2019)

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Education (3)：

2004 - 2007 Kanazawa University
2002 - 2004 Kanazawa University Graduate School of Natural Science and Technology
1998 - 2002 Kanazawa Uiversity

Professional career (1)：

Work history (6)：

2017/07 - 現在 Kanazawa University Graduate School of Medical Science Lecuturer
2016/09 - 2017/06 Kanazawa University Graduate School of Medical Science Department of Cellular and Molecular Function Analysis Assistant professor
2012/10/01 - 2016/08/31 Kanazawa University Assistant Professor
2010/02/01 - 2012/08/31 University of California, Davis Department of Nutrition Postdoctoral fellow
2008/04 - 2010/01 Kanazawa University Graduate School of Natural Science Assistant Professor

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Association Membership(s) (3)：

The Japanese Biochemical Society , Japanese Association for Protein Phosphatase Research , The Japan Society of Hepatology

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