Rchr
J-GLOBAL ID：200901056275675672   Update date: Apr. 18, 2024

Yamada Haruki

ヤマダ ハルキ | Yamada Haruki
Affiliation and department：
Kitasato University

About Kitasato University


Other affiliations (1)：
Research field  (5)： Environmental and pharmaceutical development resources ,  Internal medicine - General ,  Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (8)： Neglected Diseases ,  Global Health ,  Kampo Medicine ,  糖質生化学 ,  天然物資源系薬学 ,  和漢薬物学 ,  Bioorganic chemistry ,  Pharmaceutical biological Chemistry
Research theme for competitive and other funds  (21)：
  • 2013 - 2016 The screening of crude dergs to protect butyrate-induced death of colonic epithelial cells
  • 2011 - 2013 Analysis of neuroprotective effect of pigment epithelium derived factor
  • 2011 - 2012 Role of orexinergic system in the mechanism underlying an antidepressant-like effect of kososan
  • 2009 - 2011 Study on clarification of action mechanism of a Kampo medicine, Hochuekkito through immunomodulating exosome
  • 2009 - 2010 Involvement of orexin-A and neuropeptide Y in the antidepressant-like effect of kososan.
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Papers (48)：
  • Yutaka Aoyagi, Koji Fujiwara, Yoshinao Takahashi, Reiko Yano, Yukio Hitotsuyanagi, Koichi Takeya, Ritsuo Aiyama, Takeshi Matsuzaki, Shusuke Hashimoto, Aki Nishihara-Tsukashima, et al. Semisynthesis of Antitrypanosomal <i>p</i>-Quinone Analog Possesing the Komaroviquinone Pharmacophore. Chemical and Pharmaceutical Bulletin. 2022. 70. 4. 300-303
  • Tatsuya Shirahata, Rintaro Miyaishi, Tatsuki Kitazoe, Masaya Saito, Yuki Taneoka, Shuhei Hidaka, Masaki Yokoyama, Takayori Tojima, Tatsuya Katsumi, Nozomu Hirata, et al. Preparation of Tenuifolin from Polygala senega L. Root Using a Hydrolytic Continuous Flow System under High-Temperature, High-Pressure Conditions. The Journal of Organic Chemistry. 2021. 86. 23. 16268-16277
  • Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Sachiko Tanaka, Kenji Onda, Kentaro Sugiyama, Haruki Yamada, Toshihiko Hirano. Molecular mechanisms and therapeutic implications of tetrandrine and cepharanthine in T cell acute lymphoblastic leukemia and autoimmune diseases. Pharmacology & Therapeutics. 2021. 217. 107659-107659
  • Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Junichi Kusano, Ryusei Yamamoto, Hiroto Matsuda, Yoshikazu Hara, Yoshiaki Fujii, Seiichi Hayashi, Sachiko Tanaka, et al. NF-κB regulation by bisbenzylisoquinoline alkaloids in human T cells : A structure-activity relationship study. Med Chem Res. 2020. 29. 12. 2123-2129
  • Wencheng Xu, Xiaoqin Wang, Yuanchao Tu, Hiroshi Masaki, Sachiko Tanaka, Kenji Onda, Kentaro Sugiyama, Haruki Yamada, Toshihiko Hirano. Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells. Chemico-Biological Interactions. 2019. 310. 108726-108726
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MISC (541)：
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Patents (1)：
  • シリアダーゼ阻害剤
Books (46)：
  • Japanese Kampo Medicine In Traditional Medicine, (edited by S. Kayne)
    Pharmaceutical Press 2010
  • Japanese Kampo Medicine In Traditional Medicine, (edited by S. Kayne)
    Pharmaceutical Press 2010
  • Recent studies on structures and intestinal immunity modulating activities of pectins and pectic polysaccharides from medicinal herbs In Pectin and Pectinases, (edited by H. A. Schols, R.G. F. Visser and A.G. J. Voragen)
    Wageningen Academic Publishers, 2009
  • Alternative Medicine and Oriental Medicine In Search of Evidence by Scientific Elucidation, (edited by K. Minami)
    Yokendo Publishers 2009
  • Recent studies on structures and intestinal immunity modulating activities of pectins and pectic polysaccharides from medicinal herbs” In Pectin and Pectinases, (edited by H. A. Schols, R.G. F. Visser and A.G. J. Voragen)
    Wageningen Academic Publishers 2009
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Education (3)：
  • 1972 - 1975 Tokyo College of Pharmacy Graduate School of Pharmaceutical Sciences Microbiology
  • 1970 - 1972 Kitasato University Graduate School of Pharmaceutical Sciences Microbial Chemistry
  • 1965 - 1970 Tokyo College of Pharmacy School of Pharmacy
Professional career (1)：
  • Ph.D (Tokyo College of Pharmacy)
Work history (35)：
  • 2019/07 - 現在 Kitasato Research Center for Environmental Sciences Chair
  • 2019 - 現在 Tokyo University of Pharmacy and Life Sciences Archives Director
  • 2019 - 現在 Tokyo University of Pharmacy and Life Sciences Board of Directors
  • 2017/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Pharmacy Visiting Professor
  • 2013/04 - 現在 Kitasato University Professor Emeritus
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Committee career (13)：
  • 2018 - 現在 学校法人東京薬科大学 評議員
  • 2015 - 現在 公益財団法人日本薬剤師会 薬局製剤委員会委員
  • 2010 - 現在 日本臨床中医薬学会副理事長
  • 2009 - 現在 特定非営利活動法人DNDi Japan理事長
  • 1996/06 - 現在 日中医学協会評議員
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Awards (8)：
  • 2013 - 日本生薬学会生薬学会賞
  • 2012 - ローベルト・コッホ研究所名誉メダル
  • 2004 - 和漢医薬学会賞
  • 2000 - 立夫中医薬学術賞Lifu Academic Award for Chinese Medicine
  • 1999 - 中華伝統獣医学会 FU-Shi Research Award
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Association Membership(s) (10)：
CGCM Advisory Board ,  日本臨床中医薬学会 ,  日中医学協会 ,  DNDi Japan ,  中華伝統獣医学会(The Chinase Society of Traditional Vaterinary Science) ,  日本東洋医学会 ,  日本生薬学会 ,  和漢医薬学会 ,  日本糖質学会 ,  日本薬学会
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